Pneumonia prevention effects of perioperative oral management in approximately 25,000 patients following cancer surgery

• Published in: Clinical and experimental dental research 2020-04, Vol.6 (2), p.165-173
• Main Authors: Kurasawa, Yasuhiro, Maruoka, Yutaka, Sekiya, Hideki, Negishi, Akihide, Mukohyama, Hitoshi, Shigematsu, Shiro, Sugizaki, Jumpei, Karakida, Kazunari, Ohashi, Masaru, Ueno, Masayuki, Michiwaki, Yukihiro
• Format: Article
• Language: English
• Subjects: Adult; Age; Aged; Aged, 80 and over; Cancer surgery; Collaboration; Comorbidity; Dental Care - methods; Dentists; Ethics; Female; Gastric cancer; Health insurance; Healthcare-Associated Pneumonia - epidemiology; Healthcare-Associated Pneumonia - etiology; Healthcare-Associated Pneumonia - prevention & control; Humans; Hypertension; Incidence; Japan - epidemiology; Male; Middle Aged; Neoplasms - surgery; oral health; Oral Hygiene; Original; Patients; perioperative care; Perioperative Care - methods; Pneumonia; Population; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Postoperative Complications - prevention & control; Retrospective Studies; Risk Factors; Studies; Treatment Outcome; Variables
• ISSN: 2057-4347; 2057-4347
• DOI: 10.1002/cre2.264

Aim We conducted a multicenter study to explore the risk factors of developing pneumonia and the effectiveness of perioperative oral management (POM) for the prevention of pneumonia in postsurgical patients. Methods and results A survey covering eight regional hospitals was conducted over 4 years, from April 2010 to March 2014. Using the Diagnosis Procedure Combination database, a target group of 25,554 patients with cancer who underwent surgery was selected and assessed from a population of 346,563 patients without pneumonia on admission (sample population). The study compared the incidence of pneumonia and attempted to identify the significant predictive factors for its occurrence in these patients using multiple logistic regression analysis. Comparative assessment for the occurrence of pneumonia before and after POM implementation showed a significant incidence decrease after POM introduction in the target group, with no such change observed in the sample population. Multiple logistic regression analysis showed that the odds ratio for pneumonia occurrence after POM introduction was 0.44, indicating a reduced risk of pneumonia. Conclusion POM in cancer patients was indeed effective in reducing the incidence of pneumonia in hospitals and thereby helped in preventing pneumonia during hospitalization.