Alzheimer's disease treatment: The share of herbal medicines

One of the most frequent forms of dementia in neurological disorders is Alzheimer's disease (AD). It is a chronic neurodegenerative disease characterized by impaired learning and memory. Pathological symptoms as extracellular amyloid-beta (Aβ) plaques and intracellular accumulation of neurofibr...

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Bibliographic Details
Published in:Iranian journal of basic medical sciences 2021-02, Vol.24 (2), p.123-135
Main Authors: Soheili, Masoud, Karimian, Mohammad, Hamidi, Gholamali, Salami, Mahmoud
Format: Article
Language:English
Subjects:
Alzheimer's disease
crocus sativus
ginkgo biloba
ginseng
Herbal medicine
lavandula angustifolia
magnolia officinalis
melissa officinalis
Neurological disorders
Review
salvia miltiorrhiza
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Summary:One of the most frequent forms of dementia in neurological disorders is Alzheimer's disease (AD). It is a chronic neurodegenerative disease characterized by impaired learning and memory. Pathological symptoms as extracellular amyloid-beta (Aβ) plaques and intracellular accumulation of neurofibrillary tangles occur in AD. Due to the aging of the population and increased prevalence of AD, discovery of new therapeutic agents with the highest effectiveness and fewer side effect seems to be necessary. Numerous synthetic medicines such as tacrine, donepezil, galantamine, rivastigmine, memantine, glutathione, ascorbic acid, ubiquinone, ibuprofen, and ladostigil are routinely used for reduction of the symptoms and prevention of disease progression. Nowadays, herbal medicines have attracted popular attention for numerous beneficial effects with little side effects. , and have been widely used for relief of symptoms of some neurological disorders. This paper reviews the therapeutic effects of phytomedicines with prominent effects against various factors implicated in the emergence and progression of AD.
ISSN:2008-3866
2008-3874
DOI:10.22038/IJBMS.2020.50536.11512