Prevalence and antimicrobial sensitivity pattern of urinary tract infection among children with cerebral palsy, Moshi, Tanzania

• Published in: Pediatric health, medicine and therapeutics medicine and therapeutics, 2018-01, Vol.9, p.59-65
• Main Authors: Ryakitimbo, Amon, Philemon, Rune, Mazuguni, Festo, Msuya, Levina
• Format: Article
• Language: English
• Subjects: Ambulatory care facilities; Ampicillin; Analysis; Antibiotics; Antimicrobial agents; Birthdays; Bladder; Caregivers; Catheterization; Cerebral palsied children; Cerebral palsy; Children; Children & youth; Childrens health; Ciprofloxacin; Constipation; Drug resistance; E coli; Evidence-based medicine; Hospitals; Infection; Laboratories; Medical centers; Metronidazole; Moshi; Original Research; Pediatrics; Penicillin; Penicillins; Pneumonia; Rehabilitation; Staphylococcus aureus infections; Systematic review; Tanzanaia; University colleges; Urinary tract diseases; Urinary tract infection; Urinary tract infections; Urine; Urogenital system
• ISSN: 1179-9927; 1179-9927
• DOI: 10.2147/PHMT.S159766

Urinary tract infection (UTI) in children with cerebral palsy (CP) is a challenging yet common clinical condition. Children with CP bare the greatest risk of contracting UTI because of their difficulties in neuromotor control which lead to delay of bladder control, causing incomplete bladder emptying and urine retention. This was an analytical cross-sectional study that was conducted from September 2016 to March 2017 at Comprehensive Community Based Rehabilitation in Tanzania - Moshi and Kilimanjaro Christian Medical Centre Neurological Pediatrics Outpatient Clinic. All children who met the inclusion criteria were studied. Urine samples were collected at one point by catheterization, and urine dipstick and urine culture were done. Data were analyzed using SPSS version 20. A total of 99 children were enrolled in the study. The median age was 4 years (3-8 years); 53.5% were aged between 2 and 4 years. More than half were male. UTI was detected in 13.1% (n=13) of the children. Five causative agents of UTI were isolated, namely , , , , and . The two most common organisms, and , both had low sensitivity to ampicillin and co-trimoxazole while they were sensitive to ciprofloxacin and ceftriaxone. UTI is a common finding among children with CP. and are the commonest causative agents and are sensitive to ciprofloxacin and ceftriaxone but have low sensitivity to ampicillin and co-trimoxazole.