BODIPY-Based Molecules for Biomedical Applications

BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagnetic spectrum, (2) strong fluo...

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Bibliographic Details
Published in:Biomolecules (Basel, Switzerland) Switzerland), 2023-11, Vol.13 (12), p.1723
Main Authors: Das, Sarasija, Dey, Sudipto, Patra, Sanujit, Bera, Arindam, Ghosh, Totan, Prasad, Bibin, Sayala, Kapil Dev, Maji, Krishnendu, Bedi, Anjan, Debnath, Sashi
Format: Article
Language:English
Subjects:
Adenosine
BODIPY
BODIPY dyes
BODIPY-based functional materials for medical use
Cancer
Cancer therapies
Care and treatment
Cell division
Diagnosis
Diagnostic imaging
Drug development
Dyes
Equipment and supplies
fluorescent probe
Light
Lipids
Microscopy
Peptides
Photodynamic therapy
Proteins
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Summary:BODIPY (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives have attracted attention as probes in applications like imaging and sensing due to their unique properties like (1) strong absorption and emission in the visible and near-infrared regions of the electromagnetic spectrum, (2) strong fluorescence and (3) supreme photostability. They have also been employed in areas like photodynamic therapy. Over the last decade, BODIPY-based molecules have even emerged as candidates for cancer treatments. Cancer remains a significant health issue world-wide, necessitating a continuing search for novel therapeutic options. BODIPY is a flexible fluorophore with distinct photophysical characteristics and is a fascinating drug development platform. This review provides a comprehensive overview of the most recent breakthroughs in BODIPY-based small molecules for cancer or disease detection and therapy, including their functional potential.
ISSN:2218-273X
2218-273X
DOI:10.3390/biom13121723