Treatment of colon cancer in a patient with systemic lupus erythematosus: a case report

Gastrointestinal symptoms occur in approximately 50% of patients with systemic lupus erythematous with low specificity. Although it is well established that colon cancer is one of the many gastrointestinal manifestations associated with systemic lupus erythematous, the diagnosis and treatment remain...

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Bibliographic Details
Published in:BMC cancer 2018-10, Vol.18 (1), p.961-961, Article 961
Main Authors: Shi, Junfeng, Fei, Jianquan, Yi, Qingqing, Shen, Lijuan, Wan, Boshun, Chen, Yueyu, Chang, Qing
Format: Article
Language:English
Subjects:
Abdomen
Adenocarcinoma - complications
Adenocarcinoma - diagnosis
Adenocarcinoma - drug therapy
Adenocarcinoma - surgery
Adult
Anti-Inflammatory Agents - therapeutic use
Antigens
Antineoplastic Agents, Hormonal - therapeutic use
Arthritis
Blood tests
Cancer therapies
Case Report
Case reports
Chemoradiotherapy
Chemotherapy
Colectomy
Colon cancer
Colonic Neoplasms - complications
Colonic Neoplasms - diagnosis
Colonic Neoplasms - drug therapy
Colonic Neoplasms - surgery
Colonoscopy
Colorectal cancer
Female
Health sciences
Hospitals
Humans
Intestine
Laboratories
Laparoscopy
Lupus
Lupus Erythematosus, Systemic - complications
Medical imaging
Medicine
Methylprednisolone
Methylprednisolone - therapeutic use
Patients
Prednisone
Prednisone - therapeutic use
Radical resection
Surgery
Systemic lupus erythematosus
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Summary:Gastrointestinal symptoms occur in approximately 50% of patients with systemic lupus erythematous with low specificity. Although it is well established that colon cancer is one of the many gastrointestinal manifestations associated with systemic lupus erythematous, the diagnosis and treatment remains complex due to adrenal insufficiency symptoms. A 43-year-old Chinese woman with a five-year history of systemic lupus erythematous was diagnosed with colon cancer based on imaging test. A radical bowel resection was performed successfully. To avoid serious complications during surgery, prednisone was replaced with methylprednisolone therefore avoiding adrenal insufficiency. The patient was subsequently treated with mFOLFOX6 chemotherapy and recovered well. There is a lack of reports for treatment of colon cancer in patients with systemic lupus erythematous. This report provides an effective way to diagnose colon cancer in patients with systemic lupus erythematous and illustrates a successful therapy strategy for this complex medical condition.
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-018-4864-x