Antidiabetic Potential of Plants from the Caribbean Basin

Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia, insulin insufficiency or insulin resistance, and many issues, including vascular complications, glycative stress and lipid metabolism dysregulation. Natural products from plants with antihyperglycemic, hypolipid...

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Bibliographic Details
Published in:Plants (Basel) 2022-05, Vol.11 (10), p.1360
Main Authors: Méril-Mamert, Vanessa, Ponce-Mora, Alejandro, Sylvestre, Muriel, Lawrence, Genica, Bejarano, Eloy, Cebrián-Torrejón, Gerardo
Format: Article
Language:English
Subjects:
Acids
Biodiversity
Chemical Sciences
Complications
Diabetes
Diabetes mellitus
Flavonoids
Flora
Flowers & plants
Glucose
glycative stress
Herbal medicine
Hyperglycemia
Insulin
Insulin resistance
Lipid metabolism
Lipids
Medicinal plants
Medicine
Metabolic disorders
Metabolism
Metabolites
Natural products
Oxidative stress
Phytochemicals
phytocompounds
Review
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Summary:Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia, insulin insufficiency or insulin resistance, and many issues, including vascular complications, glycative stress and lipid metabolism dysregulation. Natural products from plants with antihyperglycemic, hypolipidemic, pancreatic protective, antioxidative, and insulin-like properties complement conventional treatments. Throughout this review, we summarize the current status of knowledge of plants from the Caribbean basin traditionally used to manage DM and treat its sequelae. Seven plants were chosen due to their use in Caribbean folk medicine. We summarize the antidiabetic properties of each species, exploring the pharmacological mechanisms related to their antidiabetic effect reported in vitro and in vivo. We propose the Caribbean flora as a source of innovative bioactive phytocompounds to treat and prevent DM and DM-associated complications.
ISSN:2223-7747
2223-7747
DOI:10.3390/plants11101360