Submandibular and sublingual salivary gland involvement in adenoid cystic carcinoma

Adenoid cystic carcinoma (AdCC) is a malignant salivary gland neoplasm that presents as an indolent but aggressive neoplasm. AdCC histogenesis is linked to the intercalated ducts of the salivary glands, equally affecting the major and minor glands. AdCC is associated with distant metastasis, most co...

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Bibliographic Details
Published in:Autopsy & case reports 2024, Vol.14, p.e2024500
Main Authors: Sawant, Poonam Ramnath, Dhume, Manjeeta Mahesh Sinai, Spadigam, Anita, Dhupar, Anita
Format: Article
Language:English
Subjects:
ANATOMY & MORPHOLOGY
Carcinoma, Adenoid Cystic
Clinical Case Report and Review
PATHOLOGY
Salivary Gland Diseases
Sublingual Gland
Submandibular Gland
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Summary:Adenoid cystic carcinoma (AdCC) is a malignant salivary gland neoplasm that presents as an indolent but aggressive neoplasm. AdCC histogenesis is linked to the intercalated ducts of the salivary glands, equally affecting the major and minor glands. AdCC is associated with distant metastasis, most commonly to the lungs, and a high recurrence rate. AdCC accounts for 4.2% of all tumors. About 55% of all reported cases affect the submandibular gland, and around 50% of AdCC cases occur in the minor salivary glands. The present review describes a case of AdCC which presented a single nodular swelling on the right side involving the floor of the mouth. It also consolidates the histopathological profile of a case of AdCC with all the relevant histopathological features.
ISSN:2236-1960
2236-1960
DOI:10.4322/acr.2024.500