Community pharmacists’ knowledge and awareness about isotretinoin therapy and its dispensing practice in Jordan

• Published in: Heliyon 2023-11, Vol.9 (11), p.e22354-e22354, Article e22354
• Main Authors: Jarab, Anan S., Al-Azzam, Sayer I., Al-Mutairi, Shriefa, Abu Heshmeh, Shrouq, Mukattash, Tareq L., AL-Qerem, Walid, Beiram, Rami, Aburuz, Salah
• Format: Article
• Language: English
• Subjects: Awareness; Dispensing practice; Isotretinoin; Knowledge; Pharmacists; Side effects
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2023.e22354

A validated self-reported questionnaire was used to evaluate pharmacists' knowledge about isotretinoin and their awareness of isotretinoin dispensing practice. The majority were not able to recognize the initial dose of isotretinoin, the potential side effects such as dyslipidemia and liver toxicity, the potential interaction with tetracycline and Vitamin A and the contraindications of isotretinoin. Around 41.3 % of the pharmacists dispensed isotretinoin without a prescription, and the majority did not recognize that isotretinoin should be dispensed for only 30 days, should not be dispensed without an emphasis on the appropriate indication, and did not know the appropriate duration of isotretinoin therapy. Male gender and postgraduate degree were associated with better awareness, while increased work experience and postgraduate degree were associated with better knowledge about isotretinoin therapy. Nevertheless, both male and female pharmacists demonstrated equivalent knowledge levels. The current study demonstrates the need to implement educational programs to improve pharmacists' knowledge and awareness about isotretinoin and its dispensing practice.