Association of healthy lifestyle score with all-cause mortality and life expectancy: a city-wide prospective cohort study of cancer survivors

Background Adherence to a healthy lifestyle could reduce the cancer mortality in the western population. We conducted a city-wide prospective study in China investigating the association of a healthy lifestyle score with all-cause mortality and the life expectancy in cancer survivors. Methods This p...

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Bibliographic Details
Published in:BMC medicine 2021-07, Vol.19 (1), p.1-158, Article 158
Main Authors: Sun, Ce, Li, Ke, Xu, Huan, Wang, Xiangjun, Qin, Pengzhe, Wang, Suixiang, Liang, Boheng, Xu, Lin
Format: Article
Language:English
Subjects:
Age groups
Alcohol use
Behavior
Body mass index
Cancer
Cancer survivor
Cancer survivors
Cancer therapies
Chemotherapy
China
Chinese medicine
Cohort analysis
Confidence intervals
Health aspects
Health behavior
Health care
Health promotion
Healthy lifestyle
Life expectancy
Life span
Life style
Lifestyles
Medical records
Mortality
Municipal finance
Physical activity
Radiation therapy
Risk factors
Sleep
Smoking
Statistical analysis
Survival
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Summary:Background Adherence to a healthy lifestyle could reduce the cancer mortality in the western population. We conducted a city-wide prospective study in China investigating the association of a healthy lifestyle score with all-cause mortality and the life expectancy in cancer survivors. Methods This prospective cohort study included 46,120 surviving patients who were firstly diagnosed with cancer in Guangzhou. Five low-risk lifestyle factors including never smoking, never alcohol use, regular physical activity ([greater than or equai to] 2 h/week), sufficient sleep ([greater than or equai to] 6 h/day), and normal or high BMI ([greater than or equai to] 18.5 kg/m.sup.2) were assessed and a lifestyle score (0-5, a higher score indicates healthier lifestyle) was generated. Hazard ratios (HRs) of all-cause mortality and the life expectancy by levels of the lifestyle scores were estimated. Results Of 46,120 cancer survivors registered from 2010 to 2017, during an average follow-up of 4.3 years (200,285 person-years), 15,209 deaths were recorded. Adjusted HRs for mortality in cancer survivors with lifestyle score of 0-2, versus 5, were 2.59 (95% confidence interval (CI): 2.03-3.30) in women, 1.91 (95%CI 1.77-2.05) in men, 2.28 (95%CI 2.03-2.55) in those aged
ISSN:1741-7015
1741-7015
DOI:10.1186/s12916-021-02024-2