Normal parathyroid hormone and non‐proliferative diabetic retinopathy in patients with type 2 diabetes

Aims/Introduction To investigate the associations between parathyroid hormone (PTH) and non‐proliferative diabetic retinopathy (NPDR) in patients with type 2 diabetes mellitus. Materials and Methods Data were collected from 2,322 patients with type 2 diabetes mellitus in hospital between 2017 and 20...

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Bibliographic Details
Published in:Journal of diabetes investigation 2021-07, Vol.12 (7), p.1220-1227
Main Authors: Sun, Shengnan, Wang, Yahao, Ma, Wenru, Cheng, Bingfei, Dong, Bingzi, Zhao, Yuhang, Hu, Jianxia, Zhou, Yue, Huang, Yajing, Wei, Fanxiang, Wang, Yangang
Format: Article
Language:English
Subjects:
Aged
Blood pressure
Cholesterol
Clinical Trial
Creatinine
Cross-Sectional Studies
Databases, Factual
Diabetes
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetic retinopathy
Diabetic Retinopathy - blood
Diabetic Retinopathy - epidemiology
Diabetic Retinopathy - etiology
Electrolytes
Fasting
Female
Glucose
Humans
Inpatients - statistics & numerical data
Laboratories
Logistic Models
Male
Middle Aged
Odds Ratio
Parathyroid
Parathyroid hormone
Parathyroid Hormone - blood
Patients
Plasma
Prevalence
Retinopathy
Retrospective Studies
Risk Factors
Thyroid gland
Type 2 diabetes
Uric acid
Women
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Summary:Aims/Introduction To investigate the associations between parathyroid hormone (PTH) and non‐proliferative diabetic retinopathy (NPDR) in patients with type 2 diabetes mellitus. Materials and Methods Data were collected from 2,322 patients with type 2 diabetes mellitus in hospital between 2017 and 2019. The odds ratio (OR) and the corresponding 95% confidence interval related to the quartiles of PTH were obtained by logistic regression analysis after adjusting the potential confounding variation. Results The patients were stratified into quartiles (Q1–Q4) based on the PTH levels, with the cut‐off limits of ≤23.74, 23.74–29.47, 29.47–37.30 and >37.30 pg/mL in men, and ≤24.47, 24.47–31.22, 31.22–39.49 and >39.49 pg/mL in women. The first quartile (Q1) represents the lowest quartile and the fourth quartile (Q4) is the highest. According to the quartiles (Q1–Q4), the prevalence rate of NPDR in patients showed a significantly decreasing trend (37.9%, 36.3%, 34.0% vs 24.0% in men; 43.2%, 40.5%, 31.1% vs 26.2% in women, both P 
ISSN:2040-1116
2040-1124
DOI:10.1111/jdi.13456