Catalyzing IVF outcome prediction: exploring advanced machine learning paradigms for enhanced success rate prognostication

• Published in: Frontiers in artificial intelligence 2024-11, Vol.7, p.1392611
• Main Authors: Sadegh-Zadeh, Seyed-Ali, Khanjani, Sanaz, Javanmardi, Shima, Bayat, Bita, Naderi, Zahra, Hajiyavand, Amir M
• Format: Article
• Language: English
• Subjects: Artificial Intelligence; data preprocessing; feature engineering; hyperparameter tuning; in vitro fertilization; machine learning; predictive modeling
• ISSN: 2624-8212; 2624-8212
• DOI: 10.3389/frai.2024.1392611

This study addresses the research problem of enhancing Fertilization (IVF) success rate prediction by integrating advanced machine learning paradigms with gynecological expertise. The methodology involves the analysis of comprehensive datasets from 2017 to 2018 and 2010-2016. Machine learning models, including Logistic Regression, Gaussian NB, SVM, MLP, KNN, and ensemble models like Random Forest, AdaBoost, Logit Boost, RUS Boost, and RSM, were employed. Key findings reveal the significance of patient demographics, infertility factors, and treatment protocols in IVF success prediction. Notably, ensemble learning methods demonstrated high accuracy, with Logit Boost achieving an accuracy of 96.35%. The implications of this research span clinical decision support, patient counseling, and data preprocessing techniques, highlighting the potential for personalized IVF treatments and continuous monitoring. The study underscores the importance of collaboration between gynecologists and data scientists to optimize IVF outcomes. Prospective studies and external validation are suggested as future directions, promising to further revolutionize fertility treatments and offer hope to couples facing infertility challenges.