Resistance status of Anopheles gambiae s.l. to insecticides following the 2011 mass distribution campaign of long-lasting insecticidal nets (LLINs) in the Plateau Department, south-eastern Benin

In 2011, Benin's National Malaria Control Programme (NMCP) organized a nationwide mass distribution campaign of LLINs throughout the country. Following this intervention, it was important to assess whether the level of susceptibility of malaria vectors to insecticides had remained the same as c...

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Bibliographic Details
Published in:Malaria journal 2020-01, Vol.19 (1), p.26-26, Article 26
Main Authors: Sovi, Arthur, Govoétchan, Renaud, Ossé, Razaki, Koukpo, Come Z, Salako, Albert S, Syme, Thomas, Anagonou, Rodrigue, Fongnikin, Augustin, Nwangwu, Udoka C, Oké-Agbo, Frédéric, Tokponnon, Filémon, Padonou, Gil Germain, Akogbeto, Martin Codjo
Format: Article
Language:English
Subjects:
Anopheles
Anopheles gambiae
Anopheles gambiae sensu lato
Collections
DDT
Decision making
Deltamethrin
Distribution
DNA
Efficacy
Females
Forecasts and trends
Human diseases
Insecticide resistance
Insecticides
Intervention
Larvae
Malaria
MIILDs
Mortality
Mosquitoes
Mutation
Nucleotide sequence
PCR
Permethrin
Pesticide resistance
Pesticides
Pyrethroids
Resistance
Species identification
Varieties
Vector-borne diseases
Vectors
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Summary:In 2011, Benin's National Malaria Control Programme (NMCP) organized a nationwide mass distribution campaign of LLINs throughout the country. Following this intervention, it was important to assess whether the level of susceptibility of malaria vectors to insecticides had remained the same as compared to the pre-intervention period. The current study investigated this. Larval collections were conducted in Ifangni, Sakété, Pobè and Kétou districts located in Plateau department, Southeastern Benin before (2009) and after (2012-2013) LLIN distribution. Anopheles gambiae sensu lato (s.l.) larvae from the 4 study districts were reared to adulthood and WHO susceptibility tests were conducted. The insecticides tested were deltamethrin (0.05%), permethrin (0.75%), bendiocarb (0.1%) and DDT (4%). Molecular species identification as well as, the characterization of the kdr L1014F mutation were also performed in the An. gambiae s.l. complex using PCR method. Overall, a significant decrease in mortality rates of An. gambiae s.l. to deltamethrin (0.05%), permethrin (0.75%) and DDT (4%) was observed post-LLIN distribution, respectively: (100% vs 80.9%, p 
ISSN:1475-2875
1475-2875
DOI:10.1186/s12936-020-3116-0