Medication adherence in patients with cluster headache and migraine: an online survey

To examine factors for adherent and non-adherent behavior in patients with cluster headache and migraine. Adults with cluster headache or migraine were included in this anonymous online survey using a questionnaire accessed via homepages of headache support groups. Medication adherence in preventive...

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Bibliographic Details
Published in:Scientific reports 2023-03, Vol.13 (1), p.4546-10, Article 4546
Main Authors: Rimmele, Florian, Müller, Britta, Becker-Hingst, Nadine, Wegener, Sophia, Rimmele, Stefanie, Kropp, Peter, Jürgens, Tim P.
Format: Article
Language:English
Subjects:
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692/617
Adult
Cluster Headache - drug therapy
Comorbidity
Drugs
Headache
Headaches
Humanities and Social Sciences
Humans
Medical treatment
Medication Adherence
Migraine
Migraine Disorders - therapy
multidisciplinary
Patient compliance
Patients
Science
Science (multidisciplinary)
Side effects
Socioeconomics
Surveys
Surveys and Questionnaires
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Summary:To examine factors for adherent and non-adherent behavior in patients with cluster headache and migraine. Adults with cluster headache or migraine were included in this anonymous online survey using a questionnaire accessed via homepages of headache support groups. Medication adherence in preventive treatment was measured with the Medication Adherence Report Scale (MARS-D). Factors for non-adherent behavior were examined (subjective socioeconomic status, psychological comorbidities, self-efficacy, coping, side effects, expectations of treatment, information on medical treatment, and trust in the physician/treatment concept). 200 participants (n = 58 with cluster headache, n = 142 with migraine) were included. The rate of medication adherence in preventive treatment was 32.8% for participants with cluster headache and 20.4% for migraine. The most common reasons for low adherence in participants with cluster headache were altering the prescribed medication dose (34%) or taking less than instructed (14%), which was mostly due to insufficient benefit from the medication or side effects. Positive expectations of medical treatment ( p  ≤ 0.05) correlated significantly with adherent behavior in cluster headache. Furthermore, the adherence-promoting factors coping and self-efficacy were more pronounced in patients with cluster headache than in those with migraine ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-30854-y