Nonpharmacological approaches for pain and symptoms of depression in people with osteoarthritis: systematic review and meta-analyses

People with osteoarthritis often experience pain and depression. These meta-analyses examined and compared nonpharmacological randomized controlled trials (RCTs) for pain and symptoms of depression in people living with osteoarthritis. RCTs published up until April 2022 were sourced by searching ele...

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Bibliographic Details
Published in:Scientific reports 2023-09, Vol.13 (1), p.15449-15449, Article 15449
Main Authors: Burley, Claire V., Casey, Anne-Nicole, Jones, Matthew D., Wright, Kemi E., Parmenter, Belinda J.
Format: Article
Language:English
Subjects:
631/443/7
692/4023/1670/407
692/699/476/1414
Aerobics
Arthritis
CRD
CRD42022338051
Databases, Factual
Depression - therapy
Exercise
Female
Humanities and Social Sciences
Humans
Male
Meditation
Mental depression
multidisciplinary
Osteoarthritis
Osteoarthritis - complications
Osteoarthritis - therapy
Pain
Physical fitness
Science
Science (multidisciplinary)
Systematic review
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Summary:People with osteoarthritis often experience pain and depression. These meta-analyses examined and compared nonpharmacological randomized controlled trials (RCTs) for pain and symptoms of depression in people living with osteoarthritis. RCTs published up until April 2022 were sourced by searching electronic databases EMBASE, PUBMED & MEDLINE, Web of Science, CINAHL and PEDro. Random-effects meta-analyses were performed to calculate pooled effect sizes (ES) and 95% confidence intervals (CI) for pain and depression. Subgroup analyses examined intervention subtypes. For pain, 29 interventions (n = 4382; 65 ± 6.9 years; 70% female), revealed a significant effect on reducing pain (ES = 0.43, 95% CI [0.25, 0.61], p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-41709-x