Automated three-dimensional activation versus conventional mapping for catheter ablation of atrial tachycardia – A prospective randomized trial

• Published in: International journal of cardiology. Heart & vasculature 2023-08, Vol.47, p.101222-101222, Article 101222
• Main Authors: Spittler, Raphael, Witte, Niclas, Hoffmann, Boris Alexander, Marx, Alexandra, Mollnau, Hanke, Quesada-Ocete, Blanca, Konrad, Torsten, Rostock, Thomas
• Format: Article
• Language: English
• Subjects: Ablation; Arrhythmia recurrence; Atrial tachycardia; Electroanatomic map; Original Paper
• ISSN: 2352-9067; 2352-9067
• DOI: 10.1016/j.ijcha.2023.101222

The automated NavX Ensite Precision latency-map (LM) algorithm aims to identify atrial tachycardia (AT) mechanisms. However, data on a direct comparison of this algorithm with conventional mapping are scarce. Patients scheduled for AT ablation were randomized to mapping with the LM- algorithm (LM group) or to conventional mapping (conventional only group: ConvO), using entrainment and local activation mapping techniques. Several outcomes were exploratively analyzed. Primary endpoint was intraprocedural AT Termination. If AT termination with only automated 3D-Mapping failed, additional conventional methods were applied (conversion). A total of 63 patients (mean 67 years, 34 % female) were enrolled. In the LM group (n = 31), the correct AT mechanism was identified in14 patients (45 %) using the algorithm alone compared to 30 patients (94 %) with conventional methods. Time to termination of the first AT was not different between groups (LM group 34 ± 20 vs. ConvO 43.1 ± 28.3 min; p = 0.2). However, when AT termination did not occur with LM algorithm, time to termination prolonged significantly (65 ± 35 min; p = 0.01). After applying conventional methods (conversion), procedural termination rates did not differ between LM group (90 %) vs. ConvO (94 %) (p = 0.3). During a follow-up time of 20 ± 9 months, no differences were observed in clinical outcomes. In this small prospective, randomized study, theuse of the LM algorithm alone may lead to AT termination, but less accurate than conventional methods.