Induction Strategy for Locally Advanced Thymoma

Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invas...

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Bibliographic Details
Published in:Frontiers in oncology 2021-07, Vol.11, p.704220-704220
Main Authors: Zhang, Yang, Li, Zongjuan, Chen, Yixing, Tan, Lijie, Zeng, Zhaochong, Ding, Jianyong, Du, Shisuo
Format: Article
Language:English
Subjects:
induction therapy
locally advanced
neoadjuvant
Oncology
R0 resection
thymoma
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Summary:Surgery remains cornerstone for the management of thymoma. Complete surgical resection (R0), is recognized as the constant and significant factor for prognosis. However, in locally advanced (Masaoka-Koga stages III-IVa) thymomas, achieving R0 resection remains challenging due to local-regional invasion of the disease. Induction treatment, with the aim of reducing bulky tumor mass, offers new strategy to facilitate totally surgical resection. Herein, we reviewed recent progress and provided a comprehensive overview of induction strategy in locally advance thymoma.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2021.704220