Direct Modification of Microcrystalline Cellulose with Ethylenediamine for use as Adsorbent for Removal Amitriptyline Drug from Environment

• Published in: Molecules (Basel, Switzerland) Switzerland), 2017-11, Vol.22 (11), p.2039
• Main Authors: Bezerra, Roosevelt D S, Leal, Régis C, da Silva, Mateus S, Morais, Alan I S, Marques, Thiago H C, Osajima, Josy A, Meneguin, Andréia B, da S Barud, Hernane, C da Silva Filho, Edson
• Format: Article
• Language: English
• Subjects: Adsorbents; Adsorption; Amitriptyline; Amitriptyline - chemistry; Aqueous solutions; Cellulose; Cellulose - chemistry; Chemical modification; Color removal; Computer applications; Contaminants; Crystalline cellulose; Density functional theory; Differential scanning calorimetry; Drugs; Ethylenediamine; Ethylenediamines - chemistry; Fourier transforms; Hydrogen-Ion Concentration; Infrared analysis; Infrared spectroscopy; Ionic strength; Kinetics; Magnetic Resonance Spectroscopy; Metals; Models, Molecular; modified cellulose; Molecular Structure; NMR; Nuclear magnetic resonance; Pollutant removal; Temperature; Thermal analysis; Thermodynamics; Thermogravimetry; Water Pollutants, Chemical - chemistry; X-Ray Diffraction
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules22112039

Cellulose derivatives have been widely used as adsorbents for the removal of micropollutants such as drugs, dyes, and metals, due to their abundance, low cost and non-contaminating nature. In this context, several studies have been performed searching for new adsorbents (cellulose derivatives) efficient at contaminant removal from aqueous solutions. Thus, a new adsorbent was synthesized by chemical modification of cellulose with ethylenediamine in the absence of solvent and applied to the adsorption of amitriptyline (AMI) in aqueous solution. The modification reaction was confirmed by X-ray Diffraction (XRD), elemental analysis, Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetry/Differential Scanning Calorimeter (TG/DSC), solid state Nuclear Magnetic Resonance of ¹H and C (¹H-NMR and C-NMR). Moreover, the effectiveness of reaction was confirmed by computational calculations using Density Functional Theory (DFT) at level B3LYP/6-31G(d). This adsorption process was influenced by pH, time, concentration, temperature and did not show significant changes due to the ionic strength variation. Through these experiments, it was observed that the maximum adsorption capacity of AMI by CN polymer at 298 K, 300 min, and pH 7 was 87.66 ± 0.60 mg·g .