The Clinical Application Value of a Novel Chip in the Detection of Pathogens in Adult Pneumonia: A Multi-Centre Prospective Study in China

The detection of pathogenic microorganisms plays a significant role in the diagnosis and management of pneumonia that are responsible for a substantial number of deaths worldwide. However, conventional microbiological tests (CMT) have low accuracy and are time-consuming. In this study, we aim to eva...

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Bibliographic Details
Published in:Infection and drug resistance 2024-01, Vol.17, p.4843-4852
Main Authors: Zhang, Ruixue, Xu, Hui, Zhang, Xiaoxue, Xiong, Hui, Tang, Fei, Lv, Liping, Mu, Xiangdong, Tian, Wei, Cheng, Yueguang, Lu, JianRong, Nie, Xiuhong, Guo, Yang, Liu, Yingying, Zhang, Zhi, Lin, Lianjun
Format: Article
Language:English
Subjects:
chip
elderly
lamp
Original Research
pathogens
pneumonia
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Summary:The detection of pathogenic microorganisms plays a significant role in the diagnosis and management of pneumonia that are responsible for a substantial number of deaths worldwide. However, conventional microbiological tests (CMT) have low accuracy and are time-consuming. In this study, we aim to evaluate the clinical value of Chips for Complicated Infection Detection (CCID) in detecting pneumonia pathogens. This study was conducted at nine hospitals in China from January 2021 to September 2022. Respiratory samples from adult pneumonia patients were collected from each patient. CMT and CCID were performed in parallel to identify the pathogens. A total of 245 patients were included, with 73% being elderly. CCID identified pathogenic microbes in 78.0% of patients and conventional microbiological tests (CMT) in 57.1% of the patients (p
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S483256