Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation

Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against several microorganisms. In dentistry, AgNP can be applied in disinfection, prophylaxis, and prevention of infections in the oral cavity. In this work, the use of silve...

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Bibliographic Details
Published in:International journal of molecular sciences 2021-03, Vol.22 (5), p.2485
Main Authors: Fernandez, Clara Couto, Sokolonski, Ana Rita, Fonseca, Maísa Santos, Stanisic, Danijela, Araújo, Danilo Barral, Azevedo, Vasco, Portela, Ricardo Dias, Tasic, Ljubica
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antiinfectives and antibacterials
Antimicrobial activity
Antimicrobial agents
Bacteria
Biological activity
Biomedical materials
Dental materials
Dentistry
Disinfection
Drug resistance
E coli
endodontics
Fluorides
Fungi
Gold
Gram-negative bacteria
Gram-positive bacteria
Humans
Industrial development
Innovations
Metal Nanoparticles - administration & dosage
Metal Nanoparticles - chemistry
Microorganisms
Mouth - drug effects
Mouth - microbiology
Nanoparticles
Nanotechnology
Oral cavity
oral microbiology
periodontology
Permeability
Pharmaceutical industry
Product development
Prophylaxis
prosthetics
Review
Silver
Silver - chemistry
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Summary:Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against several microorganisms. In dentistry, AgNP can be applied in disinfection, prophylaxis, and prevention of infections in the oral cavity. In this work, the use of silver nanoparticles in dentistry and associated technological innovations was analyzed. The scientific literature was searched using PubMed and Scopus databases with descriptors related to the use of silver nanoparticles in dentistry, resulting in 90 open-access articles. The search for patents was restricted to the A61K code (International Patent Classification), using the same descriptors, resulting in 206 patents. The results found were ordered by dental specialties and demonstrated the incorporation of AgNPs in different areas of dentistry. In this context, the search for patents reaffirmed the growth of this technology and the dominance of the USA pharmaceutical industry over AgNPs product development. It could be concluded that nanotechnology is a promising area in dentistry with several applications.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms22052485