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Topography of retinal recovery processes in humans
The purpose of this study was to examine retinal recovery processes to pographically by the application of three flash sequences with specific interstimulus intervals. Twelve healthy subjects underwent multifocal electroretinography with a light-emitting diode stimulator. Every flash sequence consis...
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Published in: | Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2014-01, Vol.8 (default), p.2133-2139 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | The purpose of this study was to examine retinal recovery processes to pographically by the application of three flash sequences with specific interstimulus intervals.
Twelve healthy subjects underwent multifocal electroretinography with a light-emitting diode stimulator. Every flash sequence consisted of three flashes with 25 msec between the first and the second flash and 35 msec between the second and the third flash. The interval between the third and the first flash of the next step was 85 msec. The interstimulus interval-dependent amplitude reductions of the multifocal electroretinographic response for these three intervals yielded three data points that were used to determine the complete curve of the recovery kinetics.
Amplitude reductions were higher with shorter interstimulus intervals. The mean half-life periods of the recovery kinetics for the different concentric rings and all subjects were: ring 1, 29.3±5.9 msec; ring 2, 24.2±6.4 msec; ring 3, 23±4.1 msec; ring 4, 23.1±4.6 msec; and ring 5, 22.3±4.4 msec. The differences between the first and all other rings were statistically significant (P |
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ISSN: | 1177-5467 1177-5483 1177-5483 |
DOI: | 10.2147/OPTH.S49708 |