Efficacy of a WeChat-Based Multimodal Digital Transformation Management Model in New-Onset Mild to Moderate Hypertension: Randomized Clinical Trial

• Published in: Journal of medical Internet research 2023-12, Vol.25 (10304), p.e52464-e52464
• Main Authors: Wang, Yijun, Guo, Fuding, Wang, Jun, Li, Zeyan, Tan, Wuping, Xie, Mengjie, Yang, Xiaomeng, Duan, Shoupeng, Song, Lingpeng, Cheng, Siyi, Liu, Zhihao, Liu, Hengyang, Qiao, Jiaming, Wang, Yueyi, Zhou, Liping, Zhou, Xiaoya, Jiang, Hong, Yu, Lilei
• Format: Article
• Language: English
• Subjects: Antihypertensives; Anxiety; Asian People; Blood Pressure; Cardiovascular disease; Clinical research; Clinical trials; Communication; Customization; Decision making; Digital Health; Digital transformation; Disease management; Efficacy; Feedback; Health education; Health services; Hospitalization; Humans; Hypertension; Hypertension - therapy; Intervention; Lifestyles; Mental depression; Mobile Applications; Multimedia; Multimodality; Obesity; Original Paper; Patients; Physicians; Primary care; Prognosis; Quality control; Quality of Life; Questionnaires; Ratings & rankings; Risk factors; Schedules; Sleep; Telemedicine; Transformation
• ISSN: 1438-8871; 1439-4456; 1438-8871
• DOI: 10.2196/52464

The advantages of multimodal digitally transformed mobile health management for patients diagnosed with mild to moderate hypertension are not yet established. We aim to evaluate the therapeutic benefits of a novel WeChat-based multimodal digital transforming management model in mobile health blood pressure (BP) management. This randomized controlled clinical trial included 175 individuals with new-onset mild to moderate hypertension who were admitted to our center between September and October 2022. The patients were randomly assigned to either the multimodal intervention group (n=88) or the usual care group (n=87). The primary composite outcome was home and office BP differences after 6 months. The major secondary outcomes were 6-month quality-of-life scores, including the self-rating anxiety scale, self-rating depression scale, and Pittsburgh Sleep Quality Index. The mean home BP decreased from 151.74 (SD 8.02)/94.22 (SD 9.32) to 126.19 (SD 8.45)/82.28 (SD 9.26) mm Hg in the multimodal intervention group and from 150.78 (SD 7.87)/91.53 (SD 9.78) to 133.48 (SD 10.86)/84.45 (SD 9.19) mm Hg in the usual care group, with a mean difference in systolic blood pressure and diastolic blood pressure of -8.25 mm Hg (95% CI -11.71 to -4.78 mm Hg; P