The Potential Application of Aloe Barbadensis Mill. as Chinese Medicine for Constipation: Mini-Review

Mill. has a long history of medicinal use in the annals of traditional Chinese medicine, wherein it has garnered considerable renown. Its multifaceted therapeutic properties, characterized by its anti-inflammatory and antibacterial attributes, alongside its established efficacy as a laxative agent,...

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Bibliographic Details
Published in:Drug design, development and therapy development and therapy, 2024-01, Vol.18, p.307-324
Main Authors: Huang, Wei-Rui, Fang, Quan-Hui, Yu, Xiang-Bin, Ge, Wei-Hong, Yu, Yue
Format: Article
Language:English
Subjects:
Aloe
aloe barbadensis mill
Constipation
Constipation - drug therapy
Gastrointestinal agents
Health aspects
Humans
laxative
Laxatives - therapeutic use
Medicine, Chinese Traditional
Medicine, Oriental
Plant Extracts - therapeutic use
Review
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Summary:Mill. has a long history of medicinal use in the annals of traditional Chinese medicine, wherein it has garnered considerable renown. Its multifaceted therapeutic properties, characterized by its anti-inflammatory and antibacterial attributes, alongside its established efficacy as a laxative agent, have been extensively documented. This review commences with an exploration of the nomenclature, fundamental characteristics, and principal constituents of Mill. responsible for its laxative effects. Subsequently, we delve into an extensive examination of the molecular mechanisms underlying Mill.'s laxative properties, types of constipation treatments, commercially available preparations, considerations pertaining to toxicity, and its clinical applications. This review aims to serve as a comprehensive reference point for healthcare professionals and researchers, fostering an enhanced understanding of the optimal utilization of Mill. in the treatment of constipation.
ISSN:1177-8881
1177-8881
DOI:10.2147/DDDT.S446563