Pregnancy and Neonatal Outcomes in SARS-CoV-2 Infection: A Systematic Review

With the emergence of SARS-CoV-2 and its rapid spread, concerns regarding its effects on pregnancy outcomes have been growing. We reviewed 245 pregnancies complicated by maternal SARS-CoV-2 infection across 48 studies listed on PubMed and MedRxiv. The most common clinical presentations were fever (5...

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Published in:Journal of pregnancy 2020-10, Vol.2020 (2020), p.1-7
Main Authors: Ahmed, Baderledeen, Salomon, Laurent J., Chervenak, Frank, Wahbeh, Farah, Chamseddine, Reem S., Rafii, Arash
Format: Article
Language:English
Subjects:
Antiviral agents
Antiviral drugs
Asymptomatic
Betacoronavirus
Cardiac arrhythmia
Care and treatment
Cesarean section
Consolidation
Coronavirus Infections - diagnosis
Coronavirus Infections - epidemiology
Coronavirus Infections - therapy
Coronaviruses
Cough
COVID-19
Diabetes
Diagnosis
Dosage and administration
Dyspnea
Female
Fever
Health aspects
Humans
Infant, Newborn
Infections
Influenza
Laboratories
Middle East respiratory syndrome
Miscarriage
Mortality
Mothers
Neonates
Newborn babies
Obstetrics
Oxygen saturation
Pandemics
Patient outcomes
Patients
Pneumonia
Pneumonia, Viral - diagnosis
Pneumonia, Viral - epidemiology
Pneumonia, Viral - therapy
Pregnancy
Pregnancy complications
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - therapy
Pregnancy Outcome
Pregnancy, Complications of
Pregnant women
Premature birth
Respiration
Respiratory diseases
Respiratory syncytial virus
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Systematic review
Ultrasonic imaging
Viral infections
Womens health
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cited_by cdi_FETCH-LOGICAL-c635t-e327214ad845a1c533955b17de59a859cbd4464446761777d83ed231533aca73
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container_end_page 7
container_issue 2020
container_start_page 1
container_title Journal of pregnancy
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creator Ahmed, Baderledeen
Salomon, Laurent J.
Chervenak, Frank
Wahbeh, Farah
Chamseddine, Reem S.
Rafii, Arash
description With the emergence of SARS-CoV-2 and its rapid spread, concerns regarding its effects on pregnancy outcomes have been growing. We reviewed 245 pregnancies complicated by maternal SARS-CoV-2 infection across 48 studies listed on PubMed and MedRxiv. The most common clinical presentations were fever (55.9%), cough (36.3%), fatigue (11.4%), and dyspnea (12.7%). Only 4.1% of patients developed respiratory distress. Of all patients, 89.0% delivered via cesarean section (n=201), with a 33.3% rate of gestational complications, a 35.3% rate of preterm delivery, and a concerning 2.5% rate of stillbirth delivery or neonatal death. Among those tested, 6.45% of newborns were reported positive for SARS-CoV-2 infection. Relative to known viral infections, the prognosis for pregnant women with SARS-CoV-2 is good, even in the absence of specific antiviral treatment. However, neonates and acute patients, especially those with gestational or preexisting comorbidities, must be actively managed to prevent the severe outcomes being increasingly reported in the literature.
doi_str_mv 10.1155/2020/4592450
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source Wiley Online Library Open Access; Publicly Available Content Database; PubMed Central; Coronavirus Research Database
subjects Antiviral agents
Antiviral drugs
Asymptomatic
Betacoronavirus
Cardiac arrhythmia
Care and treatment
Cesarean section
Consolidation
Coronavirus Infections - diagnosis
Coronavirus Infections - epidemiology
Coronavirus Infections - therapy
Coronaviruses
Cough
COVID-19
Diabetes
Diagnosis
Dosage and administration
Dyspnea
Female
Fever
Health aspects
Humans
Infant, Newborn
Infections
Influenza
Laboratories
Middle East respiratory syndrome
Miscarriage
Mortality
Mothers
Neonates
Newborn babies
Obstetrics
Oxygen saturation
Pandemics
Patient outcomes
Patients
Pneumonia
Pneumonia, Viral - diagnosis
Pneumonia, Viral - epidemiology
Pneumonia, Viral - therapy
Pregnancy
Pregnancy complications
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - therapy
Pregnancy Outcome
Pregnancy, Complications of
Pregnant women
Premature birth
Respiration
Respiratory diseases
Respiratory syncytial virus
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Systematic review
Ultrasonic imaging
Viral infections
Womens health
title Pregnancy and Neonatal Outcomes in SARS-CoV-2 Infection: A Systematic Review
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