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The Lebanese left ventricular assist device experience, a success story despite the odds
Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients. From 2010...
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Published in: | Journal of cardiothoracic surgery 2020-07, Vol.15 (1), p.192-192, Article 192 |
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creator | Hamdan, R Fakih, S Mohammad, M Charif, F Abdallah, H Safa, S Al Ali, F Issa, M Damen, B El Zein, A Younes, M Rabah, A Saab, M |
description | Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients.
From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10 years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5 years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303 ± 213 days.
In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon. |
doi_str_mv | 10.1186/s13019-020-01235-7 |
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In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon.</description><identifier>ISSN: 1749-8090</identifier><identifier>EISSN: 1749-8090</identifier><identifier>DOI: 10.1186/s13019-020-01235-7</identifier><identifier>PMID: 32723392</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adult ; Blood & organ donations ; Cardiac patients ; Cardiomyopathy ; Congestive heart failure ; Fatalities ; FDA approval ; Female ; Health aspects ; Heart failure ; Heart Failure - mortality ; Heart Failure - physiopathology ; Heart Failure - therapy ; Heart Transplantation ; Heart-Assist Devices ; Humans ; Infections ; Lebanon - epidemiology ; Left ventricular assist devices ; Male ; Middle Aged ; Middle East ; Morbidity ; Mortality ; Organ transplantation ; Population ; Registries ; Stroke ; Surgery ; Survival ; Survival Rate - trends ; Thromboembolism ; Thrombosis ; Tissue donation ; Transplantation ; Transplants & implants ; Treatment Outcome ; Ventricle</subject><ispartof>Journal of cardiothoracic surgery, 2020-07, Vol.15 (1), p.192-192, Article 192</ispartof><rights>COPYRIGHT 2020 BioMed Central Ltd.</rights><rights>2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c563t-32b9f3eb669b05b58b1c427e10a9b351b26fb51e76958d7c95068588e2ecc6a03</citedby><cites>FETCH-LOGICAL-c563t-32b9f3eb669b05b58b1c427e10a9b351b26fb51e76958d7c95068588e2ecc6a03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388207/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2435109844?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32723392$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hamdan, R</creatorcontrib><creatorcontrib>Fakih, S</creatorcontrib><creatorcontrib>Mohammad, M</creatorcontrib><creatorcontrib>Charif, F</creatorcontrib><creatorcontrib>Abdallah, H</creatorcontrib><creatorcontrib>Safa, S</creatorcontrib><creatorcontrib>Al Ali, F</creatorcontrib><creatorcontrib>Issa, M</creatorcontrib><creatorcontrib>Damen, B</creatorcontrib><creatorcontrib>El Zein, A</creatorcontrib><creatorcontrib>Younes, M</creatorcontrib><creatorcontrib>Rabah, A</creatorcontrib><creatorcontrib>Saab, M</creatorcontrib><title>The Lebanese left ventricular assist device experience, a success story despite the odds</title><title>Journal of cardiothoracic surgery</title><addtitle>J Cardiothorac Surg</addtitle><description>Heart failure is still a leading cause of mortality and morbidity. Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients.
From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10 years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5 years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303 ± 213 days.
In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon.</description><subject>Adult</subject><subject>Blood & organ donations</subject><subject>Cardiac patients</subject><subject>Cardiomyopathy</subject><subject>Congestive heart failure</subject><subject>Fatalities</subject><subject>FDA approval</subject><subject>Female</subject><subject>Health aspects</subject><subject>Heart failure</subject><subject>Heart Failure - mortality</subject><subject>Heart Failure - physiopathology</subject><subject>Heart Failure - therapy</subject><subject>Heart Transplantation</subject><subject>Heart-Assist Devices</subject><subject>Humans</subject><subject>Infections</subject><subject>Lebanon - epidemiology</subject><subject>Left ventricular assist devices</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Middle East</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Organ transplantation</subject><subject>Population</subject><subject>Registries</subject><subject>Stroke</subject><subject>Surgery</subject><subject>Survival</subject><subject>Survival Rate - 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Assist devices are reserved for advanced heart failure patients with no other therapeutic options. We aim in this paper to describe the characteristics and outcome of Lebanese left ventricular assist device (LVAD) patients.
From 2010 till December 2019, 78 patients were implanted with assist devices at the Beirut cardiac Institute, 82 pumps were used. To the most recent follow up after 10 years, 26 patients died (34%). 24 patients of 35 (68%) survived more than 5 years. Seven patients only (9%) died during one month of surgery. One year mortality was 19% (15 patients). The leading cause of early mortality was infection, whereas cerebrovascular accidents CVA were the leading cause of late mortality. Pump thrombosis occurred in 12% of the cases. The most serious long term complication was haemorrhagic CVA. Only seven patients (9%) received heart transplantation, with a mean time on support prior to transplantation of 1303 ± 213 days.
In this manuscript we reported the characteristics and outcome of the largest population of LVAD patients in Lebanon. The survival rate was 81% at one year. These findings were comparable to the international registries except for rates of heart transplantation. More efforts should be made to encourage organ donation in Lebanon.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>32723392</pmid><doi>10.1186/s13019-020-01235-7</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Blood & organ donations Cardiac patients Cardiomyopathy Congestive heart failure Fatalities FDA approval Female Health aspects Heart failure Heart Failure - mortality Heart Failure - physiopathology Heart Failure - therapy Heart Transplantation Heart-Assist Devices Humans Infections Lebanon - epidemiology Left ventricular assist devices Male Middle Aged Middle East Morbidity Mortality Organ transplantation Population Registries Stroke Surgery Survival Survival Rate - trends Thromboembolism Thrombosis Tissue donation Transplantation Transplants & implants Treatment Outcome Ventricle |
title | The Lebanese left ventricular assist device experience, a success story despite the odds |
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