Combined Heart and Kidney Transplantation: Initial Clinical Experience

Combined solid organ transplantation is infrequently performed in Brazil. The objective of this article is to present our initial experience with combined heart and kidney transplantation. From January 2007 to December 2019, four patients were submitted to combined heart and kidney transplantation....

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Published in:Revista brasileira de cirurgia cardiovascular 2022, Vol.37 (2), p.263-267
Main Authors: Atik, Fernando Antibas, Borges, Carolina de Castro, Ulhoa, Marcelo Botelho, Chaves, Renato Bueno, Barzilai, Vitor Salvatore, Biondi, Rodrigo Santos, Almeida, Tiago Martins de, Medeiros, Isabela Novais, Cardoso, Helen Souto Siqueira
Format: Article
Language:English
Subjects:
Biopsy
Brief Communication
CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiomyopathies
Chagas Disease
Ejection fraction
Female
Heart Failure
Heart Failure - surgery
Heart surgery
Heart Transplantation
Heart transplants
Hemodialysis
Hemodynamics
Hospitals
Humans
Kidney diseases
Kidney Transplantation
Kidney transplants
Lung transplants
Male
Middle Aged
Patients
Pulmonary arteries
Renal Dialysis
SURGERY
Transplants
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Summary:Combined solid organ transplantation is infrequently performed in Brazil. The objective of this article is to present our initial experience with combined heart and kidney transplantation. From January 2007 to December 2019, four patients were submitted to combined heart and kidney transplantation. Their mean age was 55.7±4.4 years, and three (75%) patients were males. All patients had Chagas cardiomyopathy, two were hospitalized and inotrope dependent, and all patients were on preoperative dialysis (median of 12 months prior to transplant). All patients survived and were in New York Heart Association functional class I at the latest follow-up (mean 34.7±17.5 months). Mean retarded kidney graft function was 22.9±9.7 days. One patient lost the kidney graft two years after the transplant due to Polyomavirus infection. Our initial experience of combined heart and kidney transplantation was favorable in selected patients with advanced heart failure and end-stage kidney disease. It requires involvement of a dedicated multispecialty team throughout all the diagnostics and treatment steps.
ISSN:1678-9741
0102-7638
1678-9741
DOI:10.21470/1678-9741-2020-0720