Synthesis of 2-azetidinones substituted quinoline derivative

Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azeti...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the Serbian Chemical Society 2013, Vol.78 (5), p.621-625
Main Authors: Mashelkar, Uday, Jha, Mukesh, Mashelkar, Beena
Format: Article
Language:English
Subjects:
2-azetidinone
2-chloro-3-formyl quinoline
acetanilide
acid chloride
aromatic amine
tri-n-butylamine
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c187m-f355f33ab8ee26ae592348476081187028d9da690024ec7f8d2ad0acaed92b913
cites
container_end_page 625
container_issue 5
container_start_page 621
container_title Journal of the Serbian Chemical Society
container_volume 78
creator Mashelkar, Uday
Jha, Mukesh
Mashelkar, Beena
description Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones. nema
doi_str_mv 10.2298/JSC120617081M
format article
fullrecord <record><control><sourceid>doaj_cross</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_b49e3ea4940a4ac0abd5bfb7e4acf157</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_b49e3ea4940a4ac0abd5bfb7e4acf157</doaj_id><sourcerecordid>oai_doaj_org_article_b49e3ea4940a4ac0abd5bfb7e4acf157</sourcerecordid><originalsourceid>FETCH-LOGICAL-c187m-f355f33ab8ee26ae592348476081187028d9da690024ec7f8d2ad0acaed92b913</originalsourceid><addsrcrecordid>eNpVkE1LAzEYhIMoWKtH7_sHVvO5ScCLLH5UKh6q5-XN5o2mtLu6SQv117taETwNMwwPwxByzugF59ZcPixqxmnFNDXs8YBMmOG01JKzQzKhQvFSMWGPyUlKS0q5UkJOyNVi1-U3TDEVfSh4CZ-Yo49d32Eq0salHPMmoy8-NmO4ih0WHoe4hRy3eEqOAqwSnv3qlLzc3jzX9-X86W5WX8_Llhm9LoNQKggBziDyClBZLqSRuhp3jgXKjbceKjuOktjqYDwHT6EF9JY7y8SUzPZc38OyeR_iGoZd00NsfoJ-eG1gyLFdYeOkRYEgraQgoaXgvHLBaRxNYEqPrHLPaoc-pQHDH4_R5vvG5t-N4gu-2GX7</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Synthesis of 2-azetidinones substituted quinoline derivative</title><source>Publicly Available Content Database</source><source>Full-Text Journals in Chemistry (Open access)</source><source>IngentaConnect Journals</source><creator>Mashelkar, Uday ; Jha, Mukesh ; Mashelkar, Beena</creator><creatorcontrib>Mashelkar, Uday ; Jha, Mukesh ; Mashelkar, Beena</creatorcontrib><description>Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones. nema</description><identifier>ISSN: 0352-5139</identifier><identifier>EISSN: 1820-7421</identifier><identifier>DOI: 10.2298/JSC120617081M</identifier><language>eng</language><publisher>Serbian Chemical Society</publisher><subject>2-azetidinone ; 2-chloro-3-formyl quinoline ; acetanilide ; acid chloride ; aromatic amine ; tri-n-butylamine</subject><ispartof>Journal of the Serbian Chemical Society, 2013, Vol.78 (5), p.621-625</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c187m-f355f33ab8ee26ae592348476081187028d9da690024ec7f8d2ad0acaed92b913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids></links><search><creatorcontrib>Mashelkar, Uday</creatorcontrib><creatorcontrib>Jha, Mukesh</creatorcontrib><creatorcontrib>Mashelkar, Beena</creatorcontrib><title>Synthesis of 2-azetidinones substituted quinoline derivative</title><title>Journal of the Serbian Chemical Society</title><description>Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones. nema</description><subject>2-azetidinone</subject><subject>2-chloro-3-formyl quinoline</subject><subject>acetanilide</subject><subject>acid chloride</subject><subject>aromatic amine</subject><subject>tri-n-butylamine</subject><issn>0352-5139</issn><issn>1820-7421</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkE1LAzEYhIMoWKtH7_sHVvO5ScCLLH5UKh6q5-XN5o2mtLu6SQv117taETwNMwwPwxByzugF59ZcPixqxmnFNDXs8YBMmOG01JKzQzKhQvFSMWGPyUlKS0q5UkJOyNVi1-U3TDEVfSh4CZ-Yo49d32Eq0salHPMmoy8-NmO4ih0WHoe4hRy3eEqOAqwSnv3qlLzc3jzX9-X86W5WX8_Llhm9LoNQKggBziDyClBZLqSRuhp3jgXKjbceKjuOktjqYDwHT6EF9JY7y8SUzPZc38OyeR_iGoZd00NsfoJ-eG1gyLFdYeOkRYEgraQgoaXgvHLBaRxNYEqPrHLPaoc-pQHDH4_R5vvG5t-N4gu-2GX7</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Mashelkar, Uday</creator><creator>Jha, Mukesh</creator><creator>Mashelkar, Beena</creator><general>Serbian Chemical Society</general><scope>AAYXX</scope><scope>CITATION</scope><scope>DOA</scope></search><sort><creationdate>2013</creationdate><title>Synthesis of 2-azetidinones substituted quinoline derivative</title><author>Mashelkar, Uday ; Jha, Mukesh ; Mashelkar, Beena</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c187m-f355f33ab8ee26ae592348476081187028d9da690024ec7f8d2ad0acaed92b913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>2-azetidinone</topic><topic>2-chloro-3-formyl quinoline</topic><topic>acetanilide</topic><topic>acid chloride</topic><topic>aromatic amine</topic><topic>tri-n-butylamine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mashelkar, Uday</creatorcontrib><creatorcontrib>Jha, Mukesh</creatorcontrib><creatorcontrib>Mashelkar, Beena</creatorcontrib><collection>CrossRef</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of the Serbian Chemical Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mashelkar, Uday</au><au>Jha, Mukesh</au><au>Mashelkar, Beena</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis of 2-azetidinones substituted quinoline derivative</atitle><jtitle>Journal of the Serbian Chemical Society</jtitle><date>2013</date><risdate>2013</risdate><volume>78</volume><issue>5</issue><spage>621</spage><epage>625</epage><pages>621-625</pages><issn>0352-5139</issn><eissn>1820-7421</eissn><abstract>Acetanilide is converted into 2-chloro-3-formyl quinoline by reacting with DMF-POCl3 at 80-90?C and then condensed with aromatic primary amines to give Schiff bases (3a-3c). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones. nema</abstract><pub>Serbian Chemical Society</pub><doi>10.2298/JSC120617081M</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0352-5139
ispartof Journal of the Serbian Chemical Society, 2013, Vol.78 (5), p.621-625
issn 0352-5139
1820-7421
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_b49e3ea4940a4ac0abd5bfb7e4acf157
source Publicly Available Content Database; Full-Text Journals in Chemistry (Open access); IngentaConnect Journals
subjects 2-azetidinone
2-chloro-3-formyl quinoline
acetanilide
acid chloride
aromatic amine
tri-n-butylamine
title Synthesis of 2-azetidinones substituted quinoline derivative
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T21%3A29%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-doaj_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20of%202-azetidinones%20substituted%20quinoline%20derivative&rft.jtitle=Journal%20of%20the%20Serbian%20Chemical%20Society&rft.au=Mashelkar,%20Uday&rft.date=2013&rft.volume=78&rft.issue=5&rft.spage=621&rft.epage=625&rft.pages=621-625&rft.issn=0352-5139&rft.eissn=1820-7421&rft_id=info:doi/10.2298/JSC120617081M&rft_dat=%3Cdoaj_cross%3Eoai_doaj_org_article_b49e3ea4940a4ac0abd5bfb7e4acf157%3C/doaj_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c187m-f355f33ab8ee26ae592348476081187028d9da690024ec7f8d2ad0acaed92b913%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true