Bioactivity of Carrageenans in Metabolic Syndrome and Cardiovascular Diseases

The high incidence of changes in the lipid profile in the world population is supported by the adoption of a lifestyle with numerous risk factors. Dyslipidemia, the main alteration in the lipid profile, is characterized by increased concentrations of total cholesterol (TC), low-density lipoprotein c...

Full description

Saved in:
Bibliographic Details
Published in:Nutraceuticals 2022-12, Vol.2 (4), p.441-454
Main Authors: Valado, Ana, Pereira, Maria, Amaral, Mónica, Cotas, João, Pereira, Leonel
Format: Article
Language:English
Subjects:
carrageenan
dyslipidemia
HDL-C
LDL-C
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The high incidence of changes in the lipid profile in the world population is supported by the adoption of a lifestyle with numerous risk factors. Dyslipidemia, the main alteration in the lipid profile, is characterized by increased concentrations of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and decreased concentration of high-density lipoprotein cholesterol (HDL-C). These modifications in lipid metabolism are particularities of metabolic syndrome (MetS) and one of the main risk factors for the development of cardiovascular diseases (CVD), one of the main causes of death in the world. Macroalgae have a high percentage of dietary fiber, and a low percentage of lipids. Carrageenans, long-chain polysaccharides extracted from red macroalgae, are present in several foods, such as jelly. Chemically, they present several structures with different applications and purposes in the cosmetic, food, and pharmaceutical industries. The bioactive potential of carrageenans has demonstrated potential in the reduction of the levels of parameters of the lipid profile, being able to be an alternative in the reversion of MetS and, consequently, in the prevention and treatment of CVD. This review article aims to compile, evaluate, and reflect on the effect of carrageenans on lipid profile markers (TC, TG, HDL-C, LDL-C), relating them to MetS and CVD.
ISSN:1661-3821
1661-3821
DOI:10.3390/nutraceuticals2040032