Construction of pain prediction model for patients undergoing hepatic arterial chemoembolization

To construct a predictive model for pain in patients undergoing hepatic arterial chemoembolization (TACE) in interventional operating room. Through literature review and expert interviews, a questionnaire was prepared for the assessment of pain factors in patients with hepatic arterial chemoemboliza...

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Bibliographic Details
Published in:World journal of surgical oncology 2023-03, Vol.21 (1), p.100-100, Article 100
Main Authors: Song, Ping-Wei, Liu, Ye-Hui, Wang, Tao, Yu, Lei, Liu, Jing-Li
Format: Article
Language:English
Subjects:
Analgesics
Carcinoma, Hepatocellular - pathology
Carcinoma
Hepatocellular
Care and treatment
Chemoembolization
Chemoembolization, Therapeutic - adverse effects
Chemoembolization, Therapeutic - methods
Chi-square test
Decision making
Diagnosis
Disease prevention
Embolization
Humans
Literature reviews
Liver cancer
Liver diseases
Liver Neoplasms - pathology
Microspheres
Pain
Patient outcomes
Patients
Prediction model
Prediction models
Prospective Studies
Questionnaires
Regression analysis
Risk factors
Statistical tests
Surgery
Therapeutic chemoembolization
Transcatheter arterial chemoembolization
Treatment Outcome
Tumors
Veins & arteries
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Summary:To construct a predictive model for pain in patients undergoing hepatic arterial chemoembolization (TACE) in interventional operating room. Through literature review and expert interviews, a questionnaire was prepared for the assessment of pain factors in patients with hepatic arterial chemoembolization. A prospective cohort study was used to select 228 patients with hepatic arterial chemoembolization in a tertiary and first-class hospital. The data of the patients in the pain group and the non-pain group were compared, and a rapid screening prediction model was constructed by univariate analysis and logistic regression analysis, and its prediction effect was tested. Tumor size, liver cancer stage, and chemoembolization with drug-loaded microspheres and pirarubicin hydrochloride (THP) mixed with lipiodol were independent predictors of pain in patients after hepatic arterial chemoembolization. Finally, the pain prediction model after TACE was obtained. The results of Hosmer-Lemeshow test showed that the model fit was good (χ  = 13.540, p = 0.095). The area under the receiver operating characteristic curve was 0.798, p 
ISSN:1477-7819
1477-7819
DOI:10.1186/s12957-023-02986-y