Evaluation of a Commercial Device Based on Reflection Spectroscopy as an Alternative to Resonance Raman Spectroscopy in Measuring Skin Carotenoid Levels: Randomized Controlled Trial

Resonance Raman spectroscopy (RRS) has been used as a reference method for measuring skin carotenoid levels (SCL), which indicate vegetable and fruit intake. However, RRS is not an easy-to-use method in SCL measurement due to its complicated implementation. In this study, a commercial spectrophotome...

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Bibliographic Details
Published in:Sensors (Basel, Switzerland) Switzerland), 2023-09, Vol.23 (17), p.7654
Main Authors: Hwang, Jeong-Eun, Park, Jin-Young, Jung, Myoung Hoon, Eom, Kunsun, Moon, Hyun Seok, Joung, Hyojee, Kim, Yoon Jae
Format: Article
Language:English
Subjects:
Analysis
Biopsy
Blood
Body mass index
Carotenoids
Cross-sectional studies
Diet
diet intervention
evaluation
Intervention
Lasers
Light
Raman spectroscopy
reflection spectroscopy
Research ethics
resonance Raman spectroscopy
Skin
skin carotenoids
Spectrum analysis
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Summary:Resonance Raman spectroscopy (RRS) has been used as a reference method for measuring skin carotenoid levels (SCL), which indicate vegetable and fruit intake. However, RRS is not an easy-to-use method in SCL measurement due to its complicated implementation. In this study, a commercial spectrophotometer based on reflection spectroscopy (RS), which is relatively simple and inexpensive, was evaluated to confirm usability compared with RRS in measuring SCL. To investigate the agreement between RS and RRS, eighty participants were randomly assigned to a high-carotenoid diet group (21 mg/day of total carotenoids) or a control-carotenoid diet group (14 mg/day of total carotenoids) during a 6-week whole-diet intervention period and a 4-week tracking period. Strong correlations between the RS and RRS methods were observed at baseline (r = 0.944) and the entire period (r = 0.930). The rate of SCL increase was similar during the diet intervention; however, the initiation of the SCL decrease in RS was slower than in RRS during the tracking period. To confirm the agreement of RS and RRS from various perspectives, new visualization tools and indices were additionally applied and confirmed the similar response patterns of the two methods. The results indicate that the proposed RS method could be an alternative to RRS in SCL measurements.
ISSN:1424-8220
1424-8220
DOI:10.3390/s23177654