Comparing Laser-Assisted and Conventional Excision in the Management of Oral Soft Lesions: A Prospective Clinical Study

• Published in: Journal of pharmacy & bioallied science 2024-02, Vol.16 (Suppl 1), p.S859-S861
• Main Authors: Mangalekar, Sachin B, Bagde, Hiroj S, Sale, Madhuri, Jambhekar, Samidha V, Patil, Chetan, Deshmukh, Chetan V
• Format: Article
• Language: English
• Subjects: Bleeding; Clinical trials; Complications; conventional excision; laser-assisted excision; Lasers; Lesions; Medical research; Medicine, Experimental; oral soft lesions; Original; Patient satisfaction; Patients; Postoperative; procedural outcomes; Statistical analysis; Wound infection
• ISSN: 0976-4879; 0975-7406
• DOI: 10.4103/jpbs.jpbs_1061_23

Oral soft lesions represent a diverse array of pathological conditions that necessitate precise and effective treatment. Laser-assisted excision has gained prominence due to its purported benefits in terms of reduced procedural time, decreased bleeding, and improved aesthetic outcomes. However, conventional excision remains a common practice. A total of 100 patients with clinically diagnosed oral soft lesions were enrolled in this prospective study. The patients were randomly divided into two groups: the laser-assisted excision group and the conventional excision group. Demographics, lesion characteristics, and medical histories were recorded for each patient. Procedural parameters such as operative time and intraoperative bleeding were meticulously documented. The laser-assisted excision group exhibited a statistically significant reduction in procedural duration compared to the conventional excision group ( < 0.05), with mean operative times of 15.2 and 20.8 min, respectively. Intraoperative bleeding was significantly reduced in the laser-assisted group ( < 0.01), with an average blood loss of 15.7 ml, while the conventional excision group reported an average blood loss of 28.6 ml. Postoperative complications analysis demonstrated that the laser-assisted group had a lower incidence of wound infections ( < 0.05) compared to the conventional excision group (5% vs. 15%). Additionally, the laser-assisted group exhibited significantly reduced scarring ( < 0.01) as reported by both patients and clinicians. Patient satisfaction scores were consistently higher in the laser-assisted excision group, with 85% of patients reporting contentment with the procedure, in contrast to 65% in the conventional excision group. In light of the results obtained from this study, laser-assisted excision emerges as a favorable approach for the management of oral soft lesions.