Nasal displacement of retinal vessels on the optic disc in glaucoma associated with a nasally angled passage through lamina cribrosa

To investigate nasal displacement of central retinal vessel (CRV) on the optic nerve head (ONH) in glaucoma in association with its passage through lamina cribrosa (LC). This cross-sectional study included 113 eyes with glaucoma and 60 normal eyes. Horizontal spectral-domain optical coherence tomogr...

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Bibliographic Details
Published in:Scientific reports 2021-02, Vol.11 (1), p.4176-4176, Article 4176
Main Authors: Sawada, Yu, Araie, Makoto, Shibata, Hitomi, Iwase, Takeshi
Format: Article
Language:English
Subjects:
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Blood vessels
Eye
Glaucoma
Horizontal cells
Humanities and Social Sciences
multidisciplinary
Optic nerve
Retina
Science
Science (multidisciplinary)
Visual field
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Summary:To investigate nasal displacement of central retinal vessel (CRV) on the optic nerve head (ONH) in glaucoma in association with its passage through lamina cribrosa (LC). This cross-sectional study included 113 eyes with glaucoma and 60 normal eyes. Horizontal spectral-domain optical coherence tomography (SD-OCT) scans of the ONH were acquired, and point where CRV emerged on the ONH surface was defined as the position of the CRV. Next, radial scans of the ONH were acquired, and angle of the CRV passing through the LC was measured. These parameters were compared between glaucomatous and normal eyes by t -test, and their relationship with possible confounders was assessed by multiple regression analyses. In glaucoma, CRV was significantly more nasally displaced than it was in normal eyes (66.0 ± 8.6 vs. 54.3 ± 9.5, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-83720-0