Computed tomography angiographic parameters of pulmonary artery as prognostic factors of residual pulmonary hypertension after pulmonary endarterectomy

• Published in: Journal of international medical research 2021-03, Vol.49 (3), p.3000605211002024-3000605211002024
• Main Authors: Niznansky, Matus, Kavan, Jan, Zemankova, Petra, Prskavec, Tomas, Ambroz, David, Jansa, Pavel, Lindner, Jaroslav
• Format: Article
• Language: English
• Subjects: Angiography; Chronic Disease; Coronary vessels; Endarterectomy; Humans; Hypertension, Pulmonary - diagnostic imaging; Hypertension, Pulmonary - surgery; Prognosis; Pulmonary arteries; Pulmonary Artery - diagnostic imaging; Pulmonary Artery - surgery; Pulmonary Embolism - diagnostic imaging; Pulmonary Embolism - surgery; Pulmonary hypertension; Retrospective Clinical Research Report; Retrospective Studies; Tomography; Treatment Outcome
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/03000605211002024

Objectives This study aimed to retrospectively assess using computed tomography pulmonary angiography (CTPA) for predicting residual pulmonary hypertension (RPH) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary endarterectomy (PEA). Methods We retrospectively analyzed data of 131 patients with CTEPH who underwent PEA in our center (2008–2015). We measured several diameters of the pulmonary artery and thoracic aorta preoperatively. We evaluated the relationship between these measurements (and their indices) and signs of RPH represented by pulmonary artery systolic pressure (PASP) estimated by echocardiography. Results Significant correlations were observed between the aortopulmonary index and prediction of any residual hypertension and moderate/severe hypertension 1 year after PEA, and any residual hypertension and severe hypertension 2 years after PEA. The aortopulmonary index was significantly related to a reduction in PASP 1 year after the operation. A lower aortopulmonary index (≤0.88 for the ascending aorta and ≤0.64 for the descending aorta) predicted lower RPH. Conclusions Preoperative CTPA parameters can be used to assess the risk of RPH after PEA. The aortopulmonary index has significant predictive value for RPH and a reduction in PASP after PEA. Lower values of the aortopulmonary index suggest a better outcome after PEA.