Dynamics and Crosstalk between Gut Microbiota, Metabolome, and Fecal Calprotectin in Very Preterm Infants: Insights into Feeding Intolerance

Background: Feeding intolerance (FI) is a significant concern in the care of preterm infants, impacting their growth and development. We previously reported that FI is linked to lower fecal calprotectin (FC) levels. This study aims to explore the postnatal dynamics and interplay between microbiota,...

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Bibliographic Details
Published in:Nutrients 2023-11, Vol.15 (22), p.4849
Main Authors: Hong, Luyang, Huang, Yihuang, Han, Junyan, Li, Shujuan, Zhang, Lan, Jiang, Siyuan, Zhou, Qi, Cao, Xincheng, Yu, Weiyin, Yang, Yi, Hong, Shangyu, Zhou, Yufeng, Yan, Weili, Cao, Yun
Format: Article
Language:English
Subjects:
Analysis
Bacteria
Birth weight
Blood
calprotectin
Chromatography
Development and progression
Disease susceptibility
Enteral nutrition
Families & family life
Feces
feeding intolerance
Food and nutrition
Gestational age
Immune system
Infants (Premature)
Infections
Mass spectrometry
Mediation
Metabolism
Metabolites
microbiome
Microbiota
Microbiota (Symbiotic organisms)
Motility
Newborn babies
pantothenic acid
Pathogenesis
polyamine metabolites
Polyamines
Premature babies
preterm infants
Scientific imaging
Sepsis
Taxonomy
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Summary:Background: Feeding intolerance (FI) is a significant concern in the care of preterm infants, impacting their growth and development. We previously reported that FI is linked to lower fecal calprotectin (FC) levels. This study aims to explore the postnatal dynamics and interplay between microbiota, metabolic profiles, and host immunity in preterm infants with and without FI. Methods: Infants with gestational age
ISSN:2072-6643
2072-6643
DOI:10.3390/nu15224849