Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study

• Published in: Clinical, cosmetic and investigational dermatology cosmetic and investigational dermatology, 2023-01, Vol.16, p.119-123
• Main Authors: Towersey, Loan, Correia, Priscila, Fajgenbaum Feiges, Mariana, Euzébio Gonçalves Junior, José, Sant'Anna, Beatriz, Kerob, Delphine, Le Floc'h, Caroline
• Format: Article
• Language: English
• Subjects: Acids; Acne; Analysis; Care and treatment; deep cleansing gel; Females; lha; lipo hydroxy acids; Pathogenesis; Phenols; Rapid Communication; salicylic acid; Skin; truncal acne; Zinc gluconate
• ISSN: 1178-7015; 1178-7015
• DOI: 10.2147/CCID.S394123

Acne is a skin condition of the pilosebaceous unit that affects mainly the face, chest and trunk. Approximately 50% of subjects with facial acne also have acne of the trunk. This study investigated the clinical benefit of a cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% in truncal acne after 84 days of daily use. A single center, open label, non-randomized study with 51 subjects with mild to moderate truncal acne was conducted. Thirty-five (35) subjects completed the study; mean age was 23 years. Inflammatory and non-inflammatory lesions, Transepidermal water loss (TEWL) and local tolerance were assessed at baseline, Day 42 and Day 84 and total lesion count was calculated. The total lesion count was significantly reduced (p