Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study

In clinical practice, oestrogen receptor (ER) analysis is almost entirely by immunohistochemistry (IHC). ASCO/CAP recommends cut-offs of 

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Bibliographic Details
Published in:Breast cancer research : BCR 2022-09, Vol.24 (1), p.61-61, Article 61
Main Authors: Lopez-Knowles, Elena, Detre, Simone, Hills, Margaret, Schuster, Eugene F, Cheang, Maggie C U, Tovey, Holly, Kilburn, Lucy S, Bliss, Judith M, Robertson, John, Mallon, Elizabeth, Skene, Anthony, Evans, Abigail, Smith, Ian, Dowsett, Mitch
Format: Article
Language:English
Subjects:
Analysis
Aromatase
Aromatase inhibitors
Aromatase Inhibitors - pharmacology
Aromatase Inhibitors - therapeutic use
Breast cancer
Breast Neoplasms - drug therapy
Breast Neoplasms - genetics
Cancer therapies
Cloning
Endocrine therapy
ErbB-2 protein
ESR1
Estrogen
Female
Gene expression
Humans
Immunohistochemistry
Ki-67 Antigen - genetics
Ki-67 Antigen - metabolism
Ki67
Messenger RNA
mRNA
Patients
PgR
Proteins
Receptor, ErbB-2 - genetics
Receptor, ErbB-2 - metabolism
Receptors, Estrogen - genetics
Receptors, Estrogen - metabolism
Receptors, Progesterone - metabolism
RNA, Messenger - genetics
Tumors
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Description
Summary:In clinical practice, oestrogen receptor (ER) analysis is almost entirely by immunohistochemistry (IHC). ASCO/CAP recommends cut-offs of 
ISSN:1465-542X
1465-5411
1465-542X
DOI:10.1186/s13058-022-01556-6