Low-grade albuminuria and its relationship with cardiovascular disease risk in hypertensive and diabetic patients in primary health care

• Published in: BMC nephrology 2022-07, Vol.23 (1), p.1-257, Article 257
• Main Authors: de Souza, Ramon Augusto Ferreira, da Silva, Eunice Ferreira, de Oliveira, Deíse Moura, Colodette, Renata Maria, Cotta, Rosângela Minardi Mitre, da Silva, Luciana Saraiva, Moreira, Tiago Ricardo
• Format: Article
• Language: English
• Subjects: Albuminuria; Blood pressure; Cardiovascular disease; Cardiovascular diseases; Chronic illnesses; Creatinine; Data collection; Diabetes; Diabetes Mellitus; Females; Gender; Health care; Health facilities; Hemoglobin; Hypertension; Kidney diseases; Laboratories; Metabolic syndrome; Nephrology; Patients; Population; Primary care; Risk factors; Triglycerides; Urine; Womens health
• ISSN: 1471-2369; 1471-2369
• DOI: 10.1186/s12882-022-02884-7

Objective To evaluate the presence of LGA and the relationship with the 10-year risk of a cardiovascular event in hypertensive and diabetic patients in Primary Health Care. Study design The study design used is cross-sectional. Methods This study was based on the application of questionnaires, anthropometric measurements, and laboratory tests carried out from August 2017 to April 2018. Logistic regression was used to evaluate the odds ratio of the explanatory variables in relation to the highest tercile of LGA. The Framingham risk score was used to assess the 10-year risk of cardiovascular event. The comparison of this score with the LGA terciles was analyzed using ANOVA. Results An increase in the 10-year risk of cardiovascular event score was observed with an increasing LGA tercile, and this pattern prevailed after adjusting for confounding variables. Conclusion An association between LGA and the 10-year risk of cardiovascular event was observed in a representative sample of hypertensive and diabetic patients. Keywords: Cardiovascular diseases, Risk factors, Hypertension, Diabetes Mellitus, Albuminuria