The impact of laparoscopic surgery in colorectal cancer resection with respect to the development of liver metastasis in the long-term

• Published in: Journal of Coloproctology 2016-01, Vol.36 (1), p.8-15
• Main Authors: Rostirolla, Renata, Fontes, Paulo, Pinho, Mauro, Pedroso, Miguel, Masuko, Tatiana, Novelli, Paula, Lima, Renato, Sampaio, José
• Format: Article
• Language: English
• Subjects: Cirurgia laparoscópica; Colectomia vídeo-assistida; Colorectal cancer; Câncer colorretal; GASTROENTEROLOGY & HEPATOLOGY; Gastroenterology and Hepatology; Hepatic metastases; Laparoscopic surgery; Long-term results; Metástases hepáticas; Original Article; Resultados a longo prazo; SURGERY; Video-assisted colectomy
• ISSN: 2237-9363; 2317-6423; 2317-6423
• DOI: 10.1016/j.jcol.2015.12.002

Abstract Introduction Colorectal cancer (CRC) shows high incidence and mortality worldwide, particularly in Western and developed countries. The objective of this study is to evaluate the oncologic results during a minimum follow-up of 2 years of curable CRC patients submitted to laparoscopic resection in our environment, regarding to the development of hepatic metastases. Methods Medical records of 189 colon and rectal patients with potentially curable adenocarcinoma who have been submitted to laparoscopic resection have been reviewed through a retrospective cohort between January 2005 and March 2012 at a single institution regarded as reference to this type of treatment. Pearson's χ2 and Long-rank tests have been used for statistical analysis and data was analyzed by statistic package STATA version 11.0. Results The eligible population for the study was 146 patients, 91 women (62%), with a mean age of 61 ± 13 years. Minimum follow-up was 24 months, having an mean follow-up of 60 ± 27 months and an mean follow-up of global disease recurrence of 27 ± 11 months. Hepatic metastases occurred in 7.5% of the population, most from stage III, and the mean recurrence period was 25 ± 16 months. Conclusions Laparoscopic resection for potentially curable CRC in this cohort did not change the long-term incidence of hepatic metastases, considering that our results are comparable to large randomized clinical trial results. Laparoscopic resection was effective and safe for analyzed patients, regarding long-term oncologic results.