Anthropometric indicators as predictor of pre-diabetes in Indian adolescents

• Published in: Indian heart journal 2017-07, Vol.69 (4), p.474-479
• Main Authors: Pandey, Umeshwar, Midha, Tanu, Rao, Yashwant Kumar, Katiyar, Pravin, Wal, Pranay, Kaur, Samarjeet, Martolia, Dinesh Singh
• Format: Article
• Language: English
• Subjects: Adolescent; Adolescents; Anthropometry - methods; BMI; Cross-Sectional Studies; Cut-off; Glucose Intolerance - blood; Glucose Intolerance - diagnosis; Glucose Intolerance - epidemiology; Humans; India - epidemiology; Original; Pre-diabetes; Prediabetic State - diagnosis; Prediabetic State - epidemiology; Prediabetic State - physiopathology; Prevalence; Risk Factors; ROC Curve; Waist circumference; Young Adult
• ISSN: 0019-4832
• DOI: 10.1016/j.ihj.2017.06.006

In India, there are approximately 41 million diabetics to date. Impaired glucose tolerance or pre-diabetes may occur as early as adolescence. To find out the cut-off values of body mass index (BMI) and waist circumference to predict pre-diabetes in adolescents in north India. A cross-sectional study was conducted among 526 students aged 17–19 years, in the Institute of Paramedical Sciences, Chatrapati Shahuji Maharaj University, Kanpur. A pre-tested questionnaire was used and the diagnostic criteria of the American Diabetic Association were applied. Receiver operating characteristic(ROC) analysis was used to assess the cut-offs of BMI and waist circumference for predicting prediabetes. ROC analysis showed that BMI is a good predictor of prediabetes for both boys and girls.Area under the ROC curve was 0.828 for boys and 0.838 for girls, respectively. The cut-off values of BMI for predicting prediabetes were identified as ≥22.8kg/m2 in boys and ≥20.5kg/m2 in girls. Upon ROC analysis for waist circumference, it was observed that it was a good predictor of prediabetes both for boys (area under the curve 0.804) and girls (area under the curve 0.795). The cut-offs for waist circumference for predicting prediabetes were found to be ≥82.5cm for boys and ≥80.3cm for girls. BMI and waist circumference estimation can be done for early detection of prediabetes in adolescents for further diagnostic evaluation and management.