Optic Neuritis in a Patient with Seropositive Myelin Oligodendrocyte Glycoprotein Antibody During the Post-COVID-19 Period

Reports of neuro-ophthalmological manifestations and complications in patients with coronavirus disease 19 (COVID-19) are still scarce. The aim of this article is to present optic neuritis, as possible post-infectious manifestation of COVID-19. Four weeks after hospitalization for seropositive coron...

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Bibliographic Details
Published in:International medical case reports journal 2021-05, Vol.14, p.349-355
Main Authors: Zoric, Lepsa, Rajovic-Mrkic, Isidora, Colak, Emina, Miric, Dijana, Kisic, Bojana
Format: Article
Language:English
Subjects:
Antibodies
Case Report
Case reports
Coronaviruses
COVID-19
Development and progression
Disease
Edema
Enzymes
Glycoproteins
Health aspects
Immunoglobulin G
Inflammation
Laboratories
Magnetic resonance imaging
Mediation
mog antibodies
Myelin proteins
Nervous system
Optic nerve
Optic neuritis
sars-cov-2
Serology
Severe acute respiratory syndrome coronavirus 2
Viruses
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Summary:Reports of neuro-ophthalmological manifestations and complications in patients with coronavirus disease 19 (COVID-19) are still scarce. The aim of this article is to present optic neuritis, as possible post-infectious manifestation of COVID-19. Four weeks after hospitalization for seropositive coronavirus disease 19 (COVID-19), presented as bilateral bronchopneumonia, with radiology and laboratory findings also pointed to high clinical suspicion to COVID-19, a 63-year-old man developed a headache and subacute and profound visual loss on his right eye. The disease presentation was the right eye papillitis. Inflammatory parameters were normal at the time of hospitalization, and IgM and IgG for SARS-CoV-2 were still positive. After corticosteroid pulse therapy, his vision improved significantly and on follow-up visits returned to normal. All laboratory and radiology findings were unremarkable, except for antibodies against SARS-CoV-2 and myelin oligodendrocyte glycoprotein (MOG). We discuss about capacity of SARS-CoV-2 to cause optic neuritis and possible significance of MOG antibodies in similar cases. Keywords: optic neuritis, SARS-CoV-2, MOG antibodies
ISSN:1179-142X
1179-142X
DOI:10.2147/IMCRJ.S315103