Outcomes in Guideline-Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy

Background In patients with obstructive hypertrophic cardiomyopathy, surgical myectomy (SM) is indicated for severe symptoms. We sought to compare long-term outcomes of patients with obstructive hypertrophic cardiomyopathy where SM was based on guideline-recommended Class I indication (Functional Cl...

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Bibliographic Details
Published in:Journal of the American Heart Association 2021-01, Vol.10 (1), p.e016210-e016210
Main Authors: Alashi, Alaa, Smedira, Nicholas G, Hodges, Kevin, Popovic, Zoran B, Thamilarasan, Maran, Wierup, Per, Lever, Harry M, Desai, Milind Y
Format: Article
Language:English
Subjects:
earlier surgery
hypertrophic cardiomyopathy
Original Research
outcomes
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Summary:Background In patients with obstructive hypertrophic cardiomyopathy, surgical myectomy (SM) is indicated for severe symptoms. We sought to compare long-term outcomes of patients with obstructive hypertrophic cardiomyopathy where SM was based on guideline-recommended Class I indication (Functional Class or FC ≥3 or angina/exertional syncope despite maximal medical therapy) versus earlier (FC 2 and/or impaired exercise capacity on exercise echocardiography with severe obstruction). Methods and Results We studied 2268 consecutive patients (excluding
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.120.016210