Managing Persistent Subsolid Nodules in Lung Cancer: Education, Decision Making, and Impact of Interval Growth Patterns

With the popularization of lung cancer screening, many persistent subsolid nodules (SSNs) have been identified clinically, especially in Asian non-smokers. However, many studies have found that SSNs exhibit heterogeneous growth trends during long-term follow ups. This article adopted a narrative app...

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Bibliographic Details
Published in:Diagnostics (Basel) 2023-08, Vol.13 (16), p.2674
Main Authors: Liu, Yung-Chi, Liang, Chia-Hao, Wu, Yun-Ju, Chen, Chi-Shen, Tang, En-Kuei, Wu, Fu-Zong
Format: Article
Language:English
Subjects:
Cancer
Classification
Clinical decision making
Development and progression
Diagnosis
Hyperplasia
interval growth
Literature reviews
Lung cancer
Medical imaging
Medical prognosis
Medical screening
Mortality
overdiagnosis
Review
Risk factors
subsolid nodules
Systematic review
Trends
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Summary:With the popularization of lung cancer screening, many persistent subsolid nodules (SSNs) have been identified clinically, especially in Asian non-smokers. However, many studies have found that SSNs exhibit heterogeneous growth trends during long-term follow ups. This article adopted a narrative approach to extensively review the available literature on the topic to explore the definitions, rationale, and clinical application of different interval growths of subsolid pulmonary nodule management and follow-up strategies. The development of SSN growth thresholds with different growth patterns could support clinical decision making with follow-up guidelines to reduce over- and delayed diagnoses. In conclusion, using different SSN growth thresholds could optimize the follow-up management and clinical decision making of SSNs in lung cancer screening programs. This could further reduce the lung cancer mortality rate and potential harm from overdiagnosis and over management.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics13162674