Clinicopathological analysis of 5146 eyelid tumours and tumour-like lesions in an eye centre in South China, 2000–2018: a retrospective cohort study

ObjectivesTo describe the clinicopathological characteristics of patients with eyelid tumours and tumour-like lesions in South China, investigate possible factors affecting tumour constitution.DesignRetrospective cohort study.SettingAll patients diagnosed with eyelid tumours were included from a hig...

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Bibliographic Details
Published in:BMJ open 2021-01, Vol.11 (1), p.e041854-e041854
Main Authors: Wang, Linyan, Shan, Yi, Dai, Xizhe, You, Na, Shao, Ji, Pan, Xiangji, Gao, Tao, Ye, Juan
Format: Article
Language:English
Subjects:
Age
Carcinoma, Basal Cell
China - epidemiology
Classification
Cohort analysis
dermatological epidemiology
Epidemiology
Eye cancer
Eyelid Neoplasms - epidemiology
Female
Females
Head & neck cancer
Humans
Lymphoma
Male
Males
Melanoma
Ophthalmology
pathology
Patients
Regression analysis
Retrospective Studies
Skin cancer
Skin Neoplasms
Sociodemographics
Trends
Tumors
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Summary:ObjectivesTo describe the clinicopathological characteristics of patients with eyelid tumours and tumour-like lesions in South China, investigate possible factors affecting tumour constitution.DesignRetrospective cohort study.SettingAll patients diagnosed with eyelid tumours were included from a high-volume tertiary eye care centre from South China which caring for over 2000 patients per day. All biopsied specimens were reviewed by two senior pathologists and were classified according to the fourth edition of the WHO Classification of Skin Tumours.ParticipantA total of 5146 cases of eyelid lesions were reviewed from 2000 to 2018, being classified by histogenesis and pathologic diagnosis, being compared with data from previous literature containing different races.Main outcome measuresAge-specific and gender-specific incidence constitutions, time trends, tumour location, distribution in different age groups and relationship with Sociodmographic Index (SDI) were calculated.ResultsBenign tumours accounted for 85.08% (4378) of all cases, among which, nevus was most common (33.07%). Eight of top 10 benign lesions had higher occurrence in upper eyelids. The R² value of linear regression in patient annual number of benign lesions were 0.946 (p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2020-041854