Demographic and clinical characteristics of pulmonary arterial hypertension caused by schistosomiasis are indistinguishable from other etiologies

• Published in: Revista da Sociedade Brasileira de Medicina Tropical 2020-01, Vol.53, p.e20190418-e20190418
• Main Authors: Mendes, Adriano Assis, Roncal, Carlos Guilhermo Piscoya, Oliveira, Flávio Roberto Azevedo de, Albuquerque, Eugênio Soares de, Góes, Gustavo Henrique Belarmino, Piscoya, Isabelle Cecília de Vasconcellos, Sobral Filho, Dário Celestino
• Format: Article
• Language: English
• Subjects: Adult; Aged; Atrial Natriuretic Factor - blood; Biomarkers - blood; cardiopulmonary disease; Echocardiography; Female; heart failure; Humans; Major; Male; Middle Aged; Protein Precursors - blood; Pulmonary Arterial Hypertension - blood; Pulmonary Arterial Hypertension - etiology; pulmonary hypertension; Retrospective Studies; right ventricle; schistosomiasis; Schistosomiasis - complications; Socioeconomic Factors; TROPICAL MEDICINE
• ISSN: 0037-8682; 1678-9849; 1678-9849
• DOI: 10.1590/0037-8682-0418-2019

Pulmonary arterial hypertension (PAH) is a serious pulmonary circulation disease caused by several etiologies, including schistosomiasis. The present study retrospectively evaluated the clinical and hemodynamic characteristics of patients with schistosomal PAH (PAH-Sch) compared to those of non-Sch PAH patients (non-Sch PAH). Patients treated at the Pronto-Socorro Cardiológico de Pernambuco and diagnosed by right cardiac catheterization were divided into PAH-Sch and non-Sch PAH groups. Their socio-demographic and clinical characteristics, N-terminal-pro B-type natriuretic peptide (NT-proBNP), and echocardiography and hemodynamic parameters were retrospectively reviewed. Among the included 98 patients (mean age, 45 ± 14 years; 68 women [69.4%]), we found 56 PAH-Sch and 42 non-Sch PAH. The age distribution was heterogeneous in the PAH-Sch group, with patients predominantly ranging from 50-59 (p