Combined Assessment of Stress Myocardial Perfusion Cardiovascular Magnetic Resonance and Flow Measurement in the Coronary Sinus Improves Prediction of Functionally Significant Coronary Stenosis Determined by Fractional Flow Reserve in Multivessel Disease

Background Recent studies using stress‐rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR). However, its diagnostic concordance may be reduced in patients with multivessel disease. We sought to...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Heart Association 2018-02, Vol.7 (3), p.n/a
Main Authors: Nakamori, Shiro, Sakuma, Hajime, Dohi, Kaoru, Ishida, Masaki, Tanigawa, Takashi, Yamada, Akimasa, Takase, Shinichi, Nakajima, Hiroshi, Sawai, Toshiki, Masuda, Jun, Nagata, Motonori, Ichikawa, Yasutaka, Kitagawa, Kakuya, Fujii, Eitaro, Yamada, Norikazu, Ito, Masaaki
Format: Article
Language:English
Subjects:
Adenosine - administration & dosage
Aged
Blood Flow Velocity
Cardiac Catheterization
Coronary Angiography
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Coronary Sinus - diagnostic imaging
Coronary Sinus - physiopathology
coronary sinus blood flow
Coronary Stenosis - diagnostic imaging
Coronary Stenosis - physiopathology
Female
fractional flow reserve
Fractional Flow Reserve, Myocardial
Humans
Magnetic Resonance Imaging, Cine
Male
Middle Aged
multivessel coronary artery disease
Myocardial Perfusion Imaging - methods
Original Research
perfusion imaging
phase‐contrast cine cardiovascular magnetic resonance
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Severity of Illness Index
stress myocardial perfusion cardiovascular magnetic resonance
Vasodilator Agents - administration & dosage
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Recent studies using stress‐rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR). However, its diagnostic concordance may be reduced in patients with multivessel disease. We sought to evaluate the concordance of adenosine stress‐rest perfusion CMR for predicting reduced FFR, and to determine the additive value of measuring global coronary flow reserve (CFR) in the coronary sinus in multivessel disease. Methods and Results Ninety‐six patients with angiographic luminal narrowing >50% underwent comprehensive CMR study and FFR measurements in 139 coronary vessels. FFR
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.117.007736