Toxic acute hepatitis associated to the administration of prostaglandin in a dog/Hepatite toxica aguda associada a administracao de prostaglandina em cao

Prostaglandin F2[alpha] can be used in dogs to increase ejaculate volume in cases of artificial insemination, semen cryopreservation or reproductive biotechnologies. Side effects after administration of PGF2[alpha] in dogs as tachycardia, tachypnea, salivation, vomiting, diarrhea and seizures are us...

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Bibliographic Details
Published in:Ciência rural 2011-09, Vol.41 (9), p.1578-1581
Main Authors: Palumbo, Mariana Isa Poci, da Conceicao, Liliane Celita, Machado, Luiz Henrique de Araujo, Lourenco, Maria Lucia Gomes, Moreira, Sabrina Almeida, Legatti, Emerson, Gutierrez, Raquel Ribeiro, Lopes, Maria Denise
Format: Article
Language:eng ; spa
Subjects:
adverse effects
caes
Complications and side effects
Diarrhea
dogs
efeitos adversos
Hepatitis
prostaglandin F2?
prostaglandina F2?
Prostaglandins
Seizures (Medicine)
Tachycardia
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Summary:Prostaglandin F2[alpha] can be used in dogs to increase ejaculate volume in cases of artificial insemination, semen cryopreservation or reproductive biotechnologies. Side effects after administration of PGF2[alpha] in dogs as tachycardia, tachypnea, salivation, vomiting, diarrhea and seizures are usually dose-dependent. This paper reports the occurrence of acute toxic hepatitis after the application of PGF2[alpha] in a dog, and discusses the importance of using this drug with caution in dogs. Key words: prostaglandin F2[alpha], adverse effects, dogs. A prostaglandina F2[alpha] pode ser usada em caes para aumentar o volume do ejaculado em casos de inseminacao artificial, criopreservacao seminal ou biotecnologias de reproducao. Os efeitos colaterais apos a administracao da PGF2a, como taquicardia, salivacao, emese, diarreia e convulsoes geralmente sao relacionadas com a dose utilizada. Esse trabalho objetiva relatar a ocorrencia de hepatite toxica aguda apos a administracao de PGF2a em um cao, e discutir a importancia de se utilizar essa droga com cautela nessa especie. Palavras-chave: prostaglandina F2[alpha], efeitos adversos, caes.
ISSN:0103-8478
1678-4596