Design and evaluation of a metronidazole central core matrix tablet

In this paper, a study of different concentration of HPMC K 15 M exerts influence on the drug release process from a new controlled drug delivery system has been realized in order to obtain a constant release rate during a prolonged period of time, for a programmed drug release. The drug release pro...

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Bibliographic Details
Published in:Journal of advanced pharmaceutical technology and research 2010-01, Vol.1 (1), p.88-96
Main Authors: Upendra Nagaich, Vandana Chaudhary, S D Tonpay, Roopa Karki
Format: Article
Language:English
Subjects:
Controlled drug delivery system
Matrix
Metronidazole
Tablets
Online Access:Get full text
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Summary:In this paper, a study of different concentration of HPMC K 15 M exerts influence on the drug release process from a new controlled drug delivery system has been realized in order to obtain a constant release rate during a prolonged period of time, for a programmed drug release. The drug release profiles obtained for the different batches have shown an interesting relationship between the particle size of the channeling agent used and the length of different operational periods.
ISSN:2231-4040
0976-2094