Coagulation and fibrinolysis in hyperparathyroidism secondary to vitamin D deficiency

Introduction Abnormal coagulation tests have been observed in patients with primary hyperparathyroidism (HPT) suggesting a prothrombotic effect of parathyroid hormone (PTH). Vitamin D deficiency (VIDD) is the most frequent cause of secondary HPT. Aim of our study was to investigate the influence of...

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Bibliographic Details
Published in:Endocrine Connections 2018-02, Vol.7 (2), p.325-333
Main Authors: Elbers, Laura P B, Wijnberge, Marije, Meijers, Joost C M, Poland, Dennis C W, Brandjes, Dees P M, Fliers, Eric, Gerdes, Victor E A
Format: Article
Language:English
Subjects:
coagulation
fibrinolysis
parathyroid hormone
secondary hyperparathyroidism
vitamin D deficiency
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Summary:Introduction Abnormal coagulation tests have been observed in patients with primary hyperparathyroidism (HPT) suggesting a prothrombotic effect of parathyroid hormone (PTH). Vitamin D deficiency (VIDD) is the most frequent cause of secondary HPT. Aim of our study was to investigate the influence of HPT secondary to moderate-to-severe VIDD and vitamin D replacement on the coagulation and fibrinolysis system. Subjects and methods Prospective cohort study of patients with vitamin D
ISSN:2049-3614
2052-0573
2049-3614
2052-0573
DOI:10.1530/EC-17-0249