Ultrasound Stratification of Hepatic Steatosis Using Hepatorenal Index

Hepatorenal index (HRI) has been shown to be an effective, noninvasive ultrasound tool to screen patients for those with or without >5% hepatic steatosis. Objective: The aim of this study was to further refine this HRI tool in order to stratify patients according to their degree of liver steatosi...

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Bibliographic Details
Published in:Diagnostics (Basel) 2021-08, Vol.11 (8), p.1443
Main Authors: Johnson, Stephen I., Fort, Daniel, Shortt, Kenneth J., Therapondos, George, Galliano, Gretchen E., Nguyen, Theresa, Bluth, Edward I.
Format: Article
Language:English
Subjects:
Abdomen
Biopsy
Cysts
hepatology
hepatorenal index
Hydronephrosis
Kidney diseases
Liver diseases
liver fat quantification
Magnetic resonance imaging
Medical records
nonalcoholic fatty liver disease
Patients
Software
steatosis
Ultrasonic imaging
ultrasound
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Summary:Hepatorenal index (HRI) has been shown to be an effective, noninvasive ultrasound tool to screen patients for those with or without >5% hepatic steatosis. Objective: The aim of this study was to further refine this HRI tool in order to stratify patients according to their degree of liver steatosis and give direction as to which patients should undergo random liver biopsy. Methods: We conducted a retrospective review of 267 consecutive patients from 2015 to 2017 who had abdominal ultrasounds and a subsequent random liver biopsy within one month. The HRI was calculated and compared with the percent steatosis as assessed by histology. Results: An HRI of ≤1.17 corresponds with >95% positive predictive value of ≤5% steatosis. Between HRI values 1.18 and 1.39, performance of steatosis prediction is mixed. However, for values 1.37. An HRI of ≥1.4 corresponds with >95% positive predictive value of ≥10% steatosis. Conclusion: HRI is an accurate noninvasive tool to quantify degree of steatosis and guide who should undergo random liver biopsy, potentially significantly reducing the total number of necessary liver biopsies.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics11081443