Immunoglobulin G4-related disease mimicking an appendiceal neoplasm: a case report

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by chronic activation of the immune system and a tendency to form tumorous lesions. IgG4-RD is frequently characterized by the presence of tumor-like masses affecting multiple organs and is easily mistaken for...

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Bibliographic Details
Published in:Journal of international medical research 2024-06, Vol.52 (6), p.3000605241260540
Main Authors: Kim, Dongwoo, Lee, Jongwon, Jung, Minsoo, Lee, Su Lim, Yim, Kwangil, Chong, Yosep, Alam, Mohammad Rizwan, Seo, Kyung Jin
Format: Article
Language:English
Subjects:
Appendiceal Neoplasms - diagnosis
Appendiceal Neoplasms - pathology
Appendix
Appendix - diagnostic imaging
Appendix - pathology
Appendix - surgery
Case Report and Case Series
Diagnosis, Differential
Female
Gastrointestinal cancer
Humans
Immunoglobulin G - blood
Immunoglobulin G4-Related Disease - diagnosis
Immunoglobulins
Middle Aged
Tomography, X-Ray Computed
Tumors
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Summary:Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by chronic activation of the immune system and a tendency to form tumorous lesions. IgG4-RD is frequently characterized by the presence of tumor-like masses affecting multiple organs and is easily mistaken for a malignant neoplasm. However, IgG4-RD affecting the appendix is extremely rare, with only seven cases reported previously. We report the case of a woman in her early 60s who presented with insidious abdominal pain and radiological findings mimicking appendiceal neoplasms. After diagnosing appendiceal neoplasms, surgery was performed. The patient had a serum IgG4 concentration of
ISSN:0300-0605
1473-2300
1473-2300
DOI:10.1177/03000605241260540