Risk factors and prognostic analysis of microscopic positive esophageal margins after radical surgery for proximal gastric cancer

Proximal gastric cancer has been on the rise worldwide in recent years. A positive surgical margin may result in incomplete tumor and affect the prognosis of patients. This study aims to analyse the risk factors for and prognosis associated with microscopic positive esophageal margins (R1 resection)...

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Bibliographic Details
Published in:BMC gastroenterology 2024-11, Vol.24 (1), p.433-8, Article 433
Main Authors: Guo, Zhenjiang, Wang, Ning, Zhao, Guangyuan, Cui, Chaobo, Liu, Fangzhen
Format: Article
Language:English
Subjects:
Adult
Aged
Cancer patients
Cancer therapies
Care and treatment
Chemotherapy
Esophagogastric Junction - pathology
Esophagogastric Junction - surgery
Esophagus
Esophagus - pathology
Esophagus - surgery
Female
Gastrectomy - methods
Gastric cancer
Gastrointestinal surgery
Humans
Male
Margins of Excision
Medical prognosis
Medical research
Medicine, Experimental
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Neoplasm, Residual
Patients
Positive margin
Prognosis
Proximal
Regression analysis
Retrospective Studies
Risk Factors
Stomach cancer
Stomach Neoplasms - mortality
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Surgery
Survival
Survival Rate
Tumors
Citations: Items that this one cites
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Summary:Proximal gastric cancer has been on the rise worldwide in recent years. A positive surgical margin may result in incomplete tumor and affect the prognosis of patients. This study aims to analyse the risk factors for and prognosis associated with microscopic positive esophageal margins (R1 resection) after radical surgery for proximal gastric cancer patients. This was a retrospective analysis of 316 patients with proximal gastric cancer who underwent surgical resection at the Department of Gastrointestinal Surgery of Hengshui People's Hospital from January 2013 to June 2018. Patients were divided into the R1 group (n = 24) and R0 group (n = 292) according to the esophageal margin status. Differences in clinicopathological characteristics and prognosis between the two groups were compared. Tumor location at the esophagogastric junction, Borrmann type 3/4, Lauren diffuse/mixed type, margin distance 
ISSN:1471-230X
1471-230X
DOI:10.1186/s12876-024-03527-x